Agonist-induced internalization and desensitization of the apelin receptor

Apelin acts via the G protein-coupled apelin receptor (APJ) to mediate effects on cardiovascular and fluid homeostasis. G protein-coupled receptor (GPCR) trafficking has an important role in the regulation of receptor signalling pathways and cellular functions, however in the case of APJ the mechani...

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Detalles Bibliográficos
Autores principales: Pope, George R., Tilve, Sharada, McArdle, Craig A., Lolait, Stephen J., O'Carroll, Anne-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: North Holland Publishing 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062952/
https://www.ncbi.nlm.nih.gov/pubmed/27492965
http://dx.doi.org/10.1016/j.mce.2016.07.040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062952/
https://www.ncbi.nlm.nih.gov/pubmed/27492965
http://dx.doi.org/10.1016/j.mce.2016.07.040

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