Cargando…
MyoD reprogramming requires Six1 and Six4 homeoproteins: genome-wide cis-regulatory module analysis
Myogenic regulatory factors of the MyoD family have the ability to reprogram differentiated cells toward a myogenic fate. In this study, we demonstrate that Six1 or Six4 are required for the reprogramming by MyoD of mouse embryonic fibroblasts (MEFs). Using microarray experiments, we found 761 genes...
Autores principales: | Santolini, Marc, Sakakibara, Iori, Gauthier, Morgane, Ribas-Aulinas, Francesc, Takahashi, Hirotaka, Sawasaki, Tatsuya, Mouly, Vincent, Concordet, Jean-Paul, Defossez, Pierre-Antoine, Hakim, Vincent, Maire, Pascal |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062961/ https://www.ncbi.nlm.nih.gov/pubmed/27302134 http://dx.doi.org/10.1093/nar/gkw512 |
Ejemplares similares
-
Six Homeoproteins and a linc-RNA at the Fast MYH Locus Lock Fast Myofiber Terminal Phenotype
por: Sakakibara, Iori, et al.
Publicado: (2014) -
Six Homeoproteins Directly Activate Myod Expression in the Gene Regulatory Networks That Control Early Myogenesis
por: Relaix, Frédéric, et al.
Publicado: (2013) -
Six1 homeoprotein drives myofiber type IIA specialization in soleus muscle
por: Sakakibara, Iori, et al.
Publicado: (2016) -
Incomplete MyoD-induced transdifferentiation is associated with chromatin remodeling deficiencies
por: Manandhar, Dinesh, et al.
Publicado: (2017) -
Overlapping functions of SIX homeoproteins during embryonic myogenesis
por: Wurmser, Maud, et al.
Publicado: (2023)