A primary role of TET proteins in establishment and maintenance of De Novo bivalency at CpG islands

Ten Eleven Translocation (TET) protein-catalyzed 5mC oxidation not only creates novel DNA modifications, such as 5hmC, but also initiates active or passive DNA demethylation. TETs’ role in the crosstalk with specific histone modifications, however, is largely elusive. Here, we show that TET2-mediate...

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Detalles Bibliográficos
Autores principales: Kong, Lingchun, Tan, Li, Lv, Ruitu, Shi, Zhennan, Xiong, Lijun, Wu, Feizhen, Rabidou, Kimberlie, Smith, Michael, He, Celestine, Zhang, Lei, Qian, Yanyan, Ma, Duan, Lan, Fei, Shi, Yang, Shi, Yujiang Geno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062965/
https://www.ncbi.nlm.nih.gov/pubmed/27288448
http://dx.doi.org/10.1093/nar/gkw529

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