hTERT promotes tumor angiogenesis by activating VEGF via interactions with the Sp1 transcription factor

Angiogenesis is recognized as an important hallmark of cancer. Although telomerase is thought to be involved in tumor angiogenesis, the evidence and underlying mechanism remain elusive. Here, we demonstrate that human telomerase reverse transcriptase (hTERT) activates vascular epithelial growth fact...

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Detalles Bibliográficos
Autores principales: Liu, Ning, Ding, Deqiang, Hao, Wanyu, Yang, Fan, Wu, Xiaoying, Wang, Miao, Xu, Xiaoling, Ju, Zhenyu, Liu, Jun-Ping, Song, Zhangfa, Shay, Jerry W., Guo, Yunliang, Cong, Yu-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062966/
https://www.ncbi.nlm.nih.gov/pubmed/27325744
http://dx.doi.org/10.1093/nar/gkw549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062966/
https://www.ncbi.nlm.nih.gov/pubmed/27325744
http://dx.doi.org/10.1093/nar/gkw549

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