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The role of sequence context, nucleotide pool balance and stress in 2′-deoxynucleotide misincorporation in viral, bacterial and mammalian RNA
The misincorporation of 2′-deoxyribonucleotides (dNs) into RNA has important implications for the function of non-coding RNAs, the translational fidelity of coding RNAs and the mutagenic evolution of viral RNA genomes. However, quantitative appreciation for the degree to which dN misincorporation oc...
Autores principales: | Wang, Jin, Dong, Hongping, Chionh, Yok Hian, McBee, Megan E., Sirirungruang, Sasilada, Cunningham, Richard P., Shi, Pei-Yong, Dedon, Peter C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062971/ https://www.ncbi.nlm.nih.gov/pubmed/27365049 http://dx.doi.org/10.1093/nar/gkw572 |
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