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Joint Bayesian inference of risk variants and tissue-specific epigenomic enrichments across multiple complex human diseases
Genome wide association studies (GWAS) provide a powerful approach for uncovering disease-associated variants in human, but fine-mapping the causal variants remains a challenge. This is partly remedied by prioritization of disease-associated variants that overlap GWAS-enriched epigenomic annotations...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062982/ https://www.ncbi.nlm.nih.gov/pubmed/27407109 http://dx.doi.org/10.1093/nar/gkw627 |