Correlation of bistranded clustered abasic DNA lesion processing with structural and dynamic DNA helix distortion

Clustered apurinic/apyrimidinic (AP; abasic) DNA lesions produced by ionizing radiation are by far more cytotoxic than isolated AP lesion entities. The structure and dynamics of a series of seven 23-bp oligonucleotides featuring simple bistranded clustered damage sites, comprising of two AP sites, z...

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Detalles Bibliográficos
Autores principales: Bignon, Emmanuelle, Gattuso, Hugo, Morell, Christophe, Dehez, François, Georgakilas, Alexandros G., Monari, Antonio, Dumont, Elise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063003/
https://www.ncbi.nlm.nih.gov/pubmed/27587587
http://dx.doi.org/10.1093/nar/gkw773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063003/
https://www.ncbi.nlm.nih.gov/pubmed/27587587
http://dx.doi.org/10.1093/nar/gkw773

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