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Invariant death
In nematodes, environmental or physiological perturbations alter death’s scaling of time. In human cancer, genetic perturbations alter death’s curvature of time. Those changes in scale and curvature follow the constraining contours of death’s invariant geometry. I show that the constraints arise fro...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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F1000Research
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063037/ https://www.ncbi.nlm.nih.gov/pubmed/27785361 http://dx.doi.org/10.12688/f1000research.9456.1 |
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author | Frank, Steven A. |
author_facet | Frank, Steven A. |
author_sort | Frank, Steven A. |
collection | PubMed |
description | In nematodes, environmental or physiological perturbations alter death’s scaling of time. In human cancer, genetic perturbations alter death’s curvature of time. Those changes in scale and curvature follow the constraining contours of death’s invariant geometry. I show that the constraints arise from a fundamental extension to the theories of randomness, invariance and scale. A generalized Gompertz law follows. The constraints imposed by the invariant Gompertz geometry explain the tendency of perturbations to stretch or bend death’s scaling of time. Variability in death rate arises from a combination of constraining universal laws and particular biological processes. |
format | Online Article Text |
id | pubmed-5063037 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | F1000Research |
record_format | MEDLINE/PubMed |
spelling | pubmed-50630372016-10-25 Invariant death Frank, Steven A. F1000Res Research Article In nematodes, environmental or physiological perturbations alter death’s scaling of time. In human cancer, genetic perturbations alter death’s curvature of time. Those changes in scale and curvature follow the constraining contours of death’s invariant geometry. I show that the constraints arise from a fundamental extension to the theories of randomness, invariance and scale. A generalized Gompertz law follows. The constraints imposed by the invariant Gompertz geometry explain the tendency of perturbations to stretch or bend death’s scaling of time. Variability in death rate arises from a combination of constraining universal laws and particular biological processes. F1000Research 2016-08-25 /pmc/articles/PMC5063037/ /pubmed/27785361 http://dx.doi.org/10.12688/f1000research.9456.1 Text en Copyright: © 2016 Frank SA http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Frank, Steven A. Invariant death |
title | Invariant death |
title_full | Invariant death |
title_fullStr | Invariant death |
title_full_unstemmed | Invariant death |
title_short | Invariant death |
title_sort | invariant death |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063037/ https://www.ncbi.nlm.nih.gov/pubmed/27785361 http://dx.doi.org/10.12688/f1000research.9456.1 |
work_keys_str_mv | AT frankstevena invariantdeath |