Cargando…

Invariant death

In nematodes, environmental or physiological perturbations alter death’s scaling of time. In human cancer, genetic perturbations alter death’s curvature of time. Those changes in scale and curvature follow the constraining contours of death’s invariant geometry. I show that the constraints arise fro...

Descripción completa

Detalles Bibliográficos
Autor principal: Frank, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063037/
https://www.ncbi.nlm.nih.gov/pubmed/27785361
http://dx.doi.org/10.12688/f1000research.9456.1
_version_ 1782459899716829184
author Frank, Steven A.
author_facet Frank, Steven A.
author_sort Frank, Steven A.
collection PubMed
description In nematodes, environmental or physiological perturbations alter death’s scaling of time. In human cancer, genetic perturbations alter death’s curvature of time. Those changes in scale and curvature follow the constraining contours of death’s invariant geometry. I show that the constraints arise from a fundamental extension to the theories of randomness, invariance and scale. A generalized Gompertz law follows. The constraints imposed by the invariant Gompertz geometry explain the tendency of perturbations to stretch or bend death’s scaling of time. Variability in death rate arises from a combination of constraining universal laws and particular biological processes.
format Online
Article
Text
id pubmed-5063037
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher F1000Research
record_format MEDLINE/PubMed
spelling pubmed-50630372016-10-25 Invariant death Frank, Steven A. F1000Res Research Article In nematodes, environmental or physiological perturbations alter death’s scaling of time. In human cancer, genetic perturbations alter death’s curvature of time. Those changes in scale and curvature follow the constraining contours of death’s invariant geometry. I show that the constraints arise from a fundamental extension to the theories of randomness, invariance and scale. A generalized Gompertz law follows. The constraints imposed by the invariant Gompertz geometry explain the tendency of perturbations to stretch or bend death’s scaling of time. Variability in death rate arises from a combination of constraining universal laws and particular biological processes. F1000Research 2016-08-25 /pmc/articles/PMC5063037/ /pubmed/27785361 http://dx.doi.org/10.12688/f1000research.9456.1 Text en Copyright: © 2016 Frank SA http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Frank, Steven A.
Invariant death
title Invariant death
title_full Invariant death
title_fullStr Invariant death
title_full_unstemmed Invariant death
title_short Invariant death
title_sort invariant death
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063037/
https://www.ncbi.nlm.nih.gov/pubmed/27785361
http://dx.doi.org/10.12688/f1000research.9456.1
work_keys_str_mv AT frankstevena invariantdeath