Open PHACTS computational protocols for in silico target validation of cellular phenotypic screens: knowing the knowns

Phenotypic screening is in a renaissance phase and is expected by many academic and industry leaders to accelerate the discovery of new drugs for new biology. Given that phenotypic screening is per definition target agnostic, the emphasis of in silico and in vitro follow-up work is on the exploratio...

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Detalles Bibliográficos
Autores principales: Digles, D., Zdrazil, B., Neefs, J.-M., Van Vlijmen, H., Herhaus, C., Caracoti, A., Brea, J., Roibás, B., Loza, M. I., Queralt-Rosinach, N., Furlong, L. I., Gaulton, A., Bartek, L., Senger, S., Chichester, C., Engkvist, O., Evelo, C. T., Franklin, N. I., Marren, D., Ecker, G. F., Jacoby, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063042/
https://www.ncbi.nlm.nih.gov/pubmed/27774140
http://dx.doi.org/10.1039/c6md00065g

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