Cephalosporins inhibit human metallo β-lactamase fold DNA repair nucleases SNM1A and SNM1B/apollo

Bacterial metallo-β-lactamases (MBLs) are involved in resistance to β-lactam antibiotics including cephalosporins. Human SNM1A and SNM1B are MBL superfamily exonucleases that play a key role in the repair of DNA interstrand cross-links, which are induced by antitumour chemotherapeutics, and are ther...

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Detalles Bibliográficos
Autores principales: Lee, Sook Y., Brem, Jürgen, Pettinati, Ilaria, Claridge, Timothy D. W., Gileadi, Opher, Schofield, Christopher J., McHugh, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063058/
https://www.ncbi.nlm.nih.gov/pubmed/27121860
http://dx.doi.org/10.1039/c6cc00529b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063058/
https://www.ncbi.nlm.nih.gov/pubmed/27121860
http://dx.doi.org/10.1039/c6cc00529b

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