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Pain and pain tolerance in whiplash‐associated disorders: A population‐based study

BACKGROUND: Pain is a cardinal symptom in individuals with whiplash‐associated disorders (WAD). We aimed to compare pain characteristics between individuals with WAD and individuals reporting chronic pain from other causes, and to determine whether potential differences were accounted for by experim...

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Autores principales: Myrtveit, S.M., Skogen, J.C., Sivertsen, B., Steingrímsdóttir, Ó.A., Stubhaug, A., Nielsen, C.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063105/
https://www.ncbi.nlm.nih.gov/pubmed/26568528
http://dx.doi.org/10.1002/ejp.819
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author Myrtveit, S.M.
Skogen, J.C.
Sivertsen, B.
Steingrímsdóttir, Ó.A.
Stubhaug, A.
Nielsen, C.S.
author_facet Myrtveit, S.M.
Skogen, J.C.
Sivertsen, B.
Steingrímsdóttir, Ó.A.
Stubhaug, A.
Nielsen, C.S.
author_sort Myrtveit, S.M.
collection PubMed
description BACKGROUND: Pain is a cardinal symptom in individuals with whiplash‐associated disorders (WAD). We aimed to compare pain characteristics between individuals with WAD and individuals reporting chronic pain from other causes, and to determine whether potential differences were accounted for by experimental pain tolerance. METHODS: Data from the 6th Tromsø Study (2007–2008, n = 12,981) were analysed. The number of painful locations was compared between individuals with WAD and individuals reporting chronic pain from other causes using negative binomial regression, pain frequency using multinomial logistic regression and pain intensity using multiple linear regression. Differences in experimental pain tolerance (cold pressor test) were tested using Cox regression; one model compared individuals with WAD to those with chronic pain from other causes, one compared the two groups with chronic pain to individuals without chronic pain. Subsequently, regression models investigating clinical pain characteristics were adjusted for pain tolerance. RESULTS: Of individuals with WAD, 96% also reported other causes for pain. Individuals with WAD reported a higher number of painful locations [median (inter‐quartile range): 5 (3.5–7) vs. 3 (2–5), p < 0.001] and higher pain intensity (crude mean difference = 0.78, p < 0.001) than individuals with chronic pain from other causes. Pain tolerance did not differ between these two groups. Compared to individuals without chronic pain, individuals with WAD and individuals with chronic pain from other causes had reduced pain tolerance. CONCLUSIONS: Individuals with WAD report more additional causes of pain, more painful locations and higher pain intensity than individuals with chronic pain from other causes. The increased pain reporting was not accounted for by pain tolerance.
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spelling pubmed-50631052016-10-19 Pain and pain tolerance in whiplash‐associated disorders: A population‐based study Myrtveit, S.M. Skogen, J.C. Sivertsen, B. Steingrímsdóttir, Ó.A. Stubhaug, A. Nielsen, C.S. Eur J Pain Original Research BACKGROUND: Pain is a cardinal symptom in individuals with whiplash‐associated disorders (WAD). We aimed to compare pain characteristics between individuals with WAD and individuals reporting chronic pain from other causes, and to determine whether potential differences were accounted for by experimental pain tolerance. METHODS: Data from the 6th Tromsø Study (2007–2008, n = 12,981) were analysed. The number of painful locations was compared between individuals with WAD and individuals reporting chronic pain from other causes using negative binomial regression, pain frequency using multinomial logistic regression and pain intensity using multiple linear regression. Differences in experimental pain tolerance (cold pressor test) were tested using Cox regression; one model compared individuals with WAD to those with chronic pain from other causes, one compared the two groups with chronic pain to individuals without chronic pain. Subsequently, regression models investigating clinical pain characteristics were adjusted for pain tolerance. RESULTS: Of individuals with WAD, 96% also reported other causes for pain. Individuals with WAD reported a higher number of painful locations [median (inter‐quartile range): 5 (3.5–7) vs. 3 (2–5), p < 0.001] and higher pain intensity (crude mean difference = 0.78, p < 0.001) than individuals with chronic pain from other causes. Pain tolerance did not differ between these two groups. Compared to individuals without chronic pain, individuals with WAD and individuals with chronic pain from other causes had reduced pain tolerance. CONCLUSIONS: Individuals with WAD report more additional causes of pain, more painful locations and higher pain intensity than individuals with chronic pain from other causes. The increased pain reporting was not accounted for by pain tolerance. John Wiley and Sons Inc. 2015-11-16 2016-07 /pmc/articles/PMC5063105/ /pubmed/26568528 http://dx.doi.org/10.1002/ejp.819 Text en © 2015 The Authors. European Journal of Pain published by John Wiley & Sons Ltd on behalf of European Pain Federation ‐ EFIC®. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research
Myrtveit, S.M.
Skogen, J.C.
Sivertsen, B.
Steingrímsdóttir, Ó.A.
Stubhaug, A.
Nielsen, C.S.
Pain and pain tolerance in whiplash‐associated disorders: A population‐based study
title Pain and pain tolerance in whiplash‐associated disorders: A population‐based study
title_full Pain and pain tolerance in whiplash‐associated disorders: A population‐based study
title_fullStr Pain and pain tolerance in whiplash‐associated disorders: A population‐based study
title_full_unstemmed Pain and pain tolerance in whiplash‐associated disorders: A population‐based study
title_short Pain and pain tolerance in whiplash‐associated disorders: A population‐based study
title_sort pain and pain tolerance in whiplash‐associated disorders: a population‐based study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063105/
https://www.ncbi.nlm.nih.gov/pubmed/26568528
http://dx.doi.org/10.1002/ejp.819
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