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Immunoactivation induced by chronic viral infection inhibits viral replication and drives immunosuppression through sustained IFN‐I responses

Acute or chronic viral infections can lead to generalized immunosuppression. Several mechanisms, such as immunopathology of CD8(+) T cells, inhibitory receptors, or regulatory T (Treg) cells, contribute to immune dysfunction. Moreover, patients with chronic viral infections usually do not respond to...

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Detalles Bibliográficos
Autores principales:	Honke, Nadine, Shaabani, Namir, Merches, Katja, Gassa, Asmae, Kraft, Anke, Ehrhardt, Katrin, Häussinger, Dieter, Löhning, Max, Dittmer, Ulf, Hengel, Hartmut, Recher, Mike, Lang, Philipp A., Lang, Karl S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2015
Materias:	Immunity to Infection
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063111/ https://www.ncbi.nlm.nih.gov/pubmed/26507703 http://dx.doi.org/10.1002/eji.201545765

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