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Photocontrolled Exposure of Pro‐apoptotic Peptide Sequences in LOV Proteins Modulates Bcl‐2 Family Interactions

LOV domains act as biomolecular sensors for light, oxygen or the environment's redox potential. Conformational changes upon the formation of a covalent cysteinyl flavin adduct are propagated through hydrogen‐bonding networks in the core of designed hybrid phototropin LOV2 domains that incorpora...

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Detalles Bibliográficos
Autores principales: Mart, Robert J., Meah, Dilruba, Allemann, Rudolf. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063126/
https://www.ncbi.nlm.nih.gov/pubmed/26493687
http://dx.doi.org/10.1002/cbic.201500469

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