Combined Use of Oligopeptides, Fragment Libraries, and Natural Compounds: A Comprehensive Approach To Sample the Druggability of Vascular Endothelial Growth Factor

The modulation of protein–protein interactions (PPIs) is emerging as a highly promising tool to fight diseases. However, whereas an increasing number of compounds are able to disrupt peptide‐mediated PPIs efficiently, the inhibition of domain–domain PPIs appears to be much more challenging. Herein,...

Descripción completa

Detalles Bibliográficos
Autores principales: Bayó‐Puxan, Núria, Rodríguez‐Mias, Ricard, Goldflam, Michael, Kotev, Martin, Ciudad, Sonia, Hipolito, Christopher J., Varese, Monica, Suga, Hiroaki, Campos‐Olivas, Ramón, Barril, Xavier, Guallar, Víctor, Teixidó, Meritxell, García, Jesús, Giralt, Ernest
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063151/
https://www.ncbi.nlm.nih.gov/pubmed/26553526
http://dx.doi.org/10.1002/cmdc.201500467

Ejemplares similares

Ejemplares similares