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Adjusting MtDNA Quantification in Whole Blood for Peripheral Blood Platelet and Leukocyte Counts

Alterations of mitochondrial DNA copy number (mtDNAcn) in the blood (mitochondrial to nuclear DNA ratio) appear associated with several systemic diseases, including primary mitochondrial disorders, carcinogenesis, and hematologic diseases. Measuring mtDNAcn in DNA extracted from whole blood (WB) ins...

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Detalles Bibliográficos
Autores principales: Hurtado-Roca, Yamilee, Ledesma, Marta, Gonzalez-Lazaro, Monica, Moreno-Loshuertos, Raquel, Fernandez-Silva, Patricio, Enriquez, Jose Antonio, Laclaustra, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063275/
https://www.ncbi.nlm.nih.gov/pubmed/27736919
http://dx.doi.org/10.1371/journal.pone.0163770

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