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Detection of Independent Associations of Plasma Lipidomic Parameters with Insulin Sensitivity Indices Using Data Mining Methodology
OBJECTIVE: Glucolipotoxicity is a major pathophysiological mechanism in the development of insulin resistance and type 2 diabetes mellitus (T2D). We aimed to detect subtle changes in the circulating lipid profile by shotgun lipidomics analyses and to associate them with four different insulin sensit...
Autores principales: | Kopprasch, Steffi, Dheban, Srirangan, Schuhmann, Kai, Xu, Aimin, Schulte, Klaus-Martin, Simeonovic, Charmaine J., Schwarz, Peter E. H., Bornstein, Stefan R., Shevchenko, Andrej, Graessler, Juergen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063331/ https://www.ncbi.nlm.nih.gov/pubmed/27736893 http://dx.doi.org/10.1371/journal.pone.0164173 |
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