Dynamic ASXL1 Exon Skipping and Alternative Circular Splicing in Single Human Cells

Circular RNAs comprise a poorly understood new class of noncoding RNA. In this study, we used a combination of targeted deletion, high-resolution splicing detection, and single-cell sequencing to deeply probe ASXL1 circular splicing. We found that efficient circular splicing required the canonical t...

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Detalles Bibliográficos
Autores principales: Koh, Winston, Gonzalez, Veronica, Natarajan, Sivaraman, Carter, Robert, Brown, Patrick O., Gawad, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063410/
https://www.ncbi.nlm.nih.gov/pubmed/27736885
http://dx.doi.org/10.1371/journal.pone.0164085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063410/
https://www.ncbi.nlm.nih.gov/pubmed/27736885
http://dx.doi.org/10.1371/journal.pone.0164085

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