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No Overt Deficits in Aged Tau-Deficient C57Bl/6.Mapt(tm1(EGFP)Kit) GFP Knockin Mice

Several mouse lines with knockout of the tau-encoding MAPT gene have been reported in the past; they received recent attention due to reports that tau reduction prevented Aβ-induced deficits in mouse models of Alzheimer’s disease. However, the effects of long-term depletion of tau in vivo remained c...

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Detalles Bibliográficos
Autores principales:	van Hummel, Annika, Bi, Mian, Ippati, Stefania, van der Hoven, Julia, Volkerling, Alexander, Lee, Wei S., Tan, Daniel C. S., Bongers, Andre, Ittner, Arne, Ke, Yazi D., Ittner, Lars M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063411/ https://www.ncbi.nlm.nih.gov/pubmed/27736877 http://dx.doi.org/10.1371/journal.pone.0163236

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