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Refinement of the HIVAN1 Susceptibility Locus on Chr. 3A1-A3 via Generation of Sub-Congenic Strains

HIV-1 transgenic mice on the FVB/NJ background (TgFVB) represent a validated model of HIV-associated nephropathy (HIVAN). A major susceptibility locus, HIVAN1, was previously mapped to chromosome 3A1-A3 in a cross between TgFVB and CAST/EiJ (CAST) strains, and introgression of a 51.9 Mb segment enco...

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Detalles Bibliográficos
Autores principales:	Papeta, Natalia, Patel, Ami, D’Agati, Vivette D., Gharavi, Ali G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063463/ https://www.ncbi.nlm.nih.gov/pubmed/27736906 http://dx.doi.org/10.1371/journal.pone.0163860

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