Cargando…

Unilateral Carotid Body Resection in Resistant Hypertension: A Safety and Feasibility Trial

Animal and human data indicate pathological afferent signaling emanating from the carotid body that drives sympathetically mediated elevations in blood pressure in conditions of hypertension. This first-in-man, proof-of-principle study tested the safety and feasibility of unilateral carotid body res...

Descripción completa

Detalles Bibliográficos
Autores principales:	Narkiewicz, Krzysztof, Ratcliffe, Laura E.K., Hart, Emma C., Briant, Linford J.B., Chrostowska, Marzena, Wolf, Jacek, Szyndler, Anna, Hering, Dagmara, Abdala, Ana P., Manghat, Nathan, Burchell, Amy E., Durant, Claire, Lobo, Melvin D., Sobotka, Paul A., Patel, Nikunj K., Leiter, James C., Engelman, Zoar J., Nightingale, Angus K., Paton, Julian F.R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	CLINICAL RESEARCH
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063532/ https://www.ncbi.nlm.nih.gov/pubmed/27766316 http://dx.doi.org/10.1016/j.jacbts.2016.06.004

Ejemplares similares

Revelations About Carotid Body Function Through its Pathological Role in Resistant Hypertension
por: Paton, Julian F. R., et al.
Publicado: (2013)

Modelling the vascular response to sympathetic postganglionic nerve activity
por: Briant, Linford J.B., et al.
Publicado: (2015)

Utility of MRI as the primary imaging tool in hypertension
por: Burchell, Amy E, et al.
Publicado: (2014)

Insights from cardiovascular magnetic resonance imaging supporting the selfish brain hypothesis of arterial hypertension
por: Rodrigues, Jonathan C, et al.
Publicado: (2015)

Should we screen for intracranial aneurysms (IAs) in systemic hypertension at the time of cardiac magnetic resonance (CMR)?
por: Rodrigues, Jonathan C, et al.
Publicado: (2015)

ECG strain pattern in hypertension is associated with myocardial cellular expansion and diffuse interstitial fibrosis: a multi-parametric cardiac magnetic resonance study
por: Rodrigues, Jonathan C.L., et al.
Publicado: (2017)

Metabolomic Signature of Early Vascular Aging (EVA) in Hypertension
por: Polonis, Katarzyna, et al.
Publicado: (2020)

Hypertensive heart disease versus hypertrophic cardiomyopathy: multi-parametric CMR predictors beyond end-diastolic wall thickness ≥15mm
por: Rodrigues, Jonathan C, et al.
Publicado: (2016)

Epilepsy and hypertension: The possible link for sudden unexpected death in epilepsy?
por: Szczurkowska, Patrycja J., et al.
Publicado: (2021)

Electrocardiographic detection of left atrial enlargement in arterial hypertension: re-calibration against cardiac magnetic resonance
por: Rodrigues, Jonathan C, et al.
Publicado: (2016)

Improving the poor diagnostic accuracy of the ECG at detecting prognostically significant left ventricular hypertrophy in hypertensive patients
por: Rodrigues, Jonathan C, et al.
Publicado: (2015)

Phenotyping patterns of left ventricular remodeling and hypertrophy in systemic hypertension by cardiac magnetic resonance (CMR)
por: Rodrigues, Jonathan C, et al.
Publicado: (2015)

Are systolic function and ejection fraction interchangeable? New insights from cardiovascular magnetic resonance and in-vivo validation of mathematical models of LV function
por: Rodrigues, Jonathan C, et al.
Publicado: (2015)

Long-term effects of device-guided slow breathing in stable heart failure patients with reduced ejection fraction
por: Lachowska, Kamila, et al.
Publicado: (2018)

The effect of obesity on electrocardiographic detection of hypertensive left ventricular hypertrophy: recalibration against cardiac magnetic resonance
por: Rodrigues, J C L, et al.
Publicado: (2016)

Mapping the cellular electrophysiology of rat sympathetic preganglionic neurones to their roles in cardiorespiratory reflex integration: a whole cell recording study in situ
por: Stalbovskiy, Alexey O, et al.
Publicado: (2014)

Serum of obstructive sleep apnea patients impairs human coronary endothelial cell migration
por: Hoffmann, Michał, et al.
Publicado: (2015)

Comprehensive intra/extracellular myocardial structural and functional characterization of hypertensive heart disease phenotypes
por: Rodrigues, Jonathan C, et al.
Publicado: (2016)

Splanchnic Nerve Ablation for Volume Management in Heart Failure
por: Fudim, Marat, et al.
Publicado: (2022)

Cerebrovascular Variants and the Role of the Selfish Brain in Young-Onset Hypertension
por: Manghat, Nathan E., et al.
Publicado: (2022)

Comprehensive characterisation of hypertensive heart disease left ventricular phenotypes
por: Rodrigues, Jonathan C L, et al.
Publicado: (2016)

Beta-cell hubs maintain Ca(2+) oscillations in human and mouse islet simulations
por: Lei, Chon-Lok, et al.
Publicado: (2018)

Sympathetic-transduction in untreated hypertension
por: Kobetic, Matthew D., et al.
Publicado: (2021)

Early Hemodynamic Changes following Surgical Ablation of the Right Greater Splanchnic Nerve for the Treatment of Heart Failure with Preserved Ejection Fraction
por: Gajewski, Piotr, et al.
Publicado: (2022)

Glucagon secretion from pancreatic α-cells
por: Briant, Linford, et al.
Publicado: (2016)

Innervation modulates the functional connectivity between pancreatic endocrine cells
por: Yang, Yu Hsuan Carol, et al.
Publicado: (2022)

Effects of Renal Denervation on Sympathetic Activation, Blood Pressure, and Glucose Metabolism in Patients with Resistant Hypertension
por: Schlaich, Markus P., et al.
Publicado: (2012)

CPT1a-Dependent Long-Chain Fatty Acid Oxidation Contributes to Maintaining Glucagon Secretion from Pancreatic Islets
por: Briant, Linford J.B., et al.
Publicado: (2018)

Prognostic factors in patients with T1 glottic cancer treated with radiotherapy
por: Mucha-Małecka, A., et al.
Publicado: (2019)

Reduced somatostatin signalling leads to hypersecretion of glucagon in mice fed a high-fat diet
por: Kellard, Joely A., et al.
Publicado: (2020)

State-dependent control of the respiratory pattern and coupled oscillators
por: Rybak, Ilya A, et al.
Publicado: (2011)

The Big Drink Debate: perceptions of the impact of price on alcohol consumption from a large scale cross-sectional convenience survey in north west England
por: Cook, Penny A, et al.
Publicado: (2011)

Increased intrinsic excitability of muscle vasoconstrictor preganglionic neurons may contribute to the elevated sympathetic activity in hypertensive rats
por: Briant, Linford J. B., et al.
Publicado: (2014)

Functional identification of islet cell types by electrophysiological fingerprinting
por: Briant, Linford J. B., et al.
Publicado: (2017)

Humanized Mice Are Instrumental to the Study of Plasmodium falciparum Infection
por: Tyagi, Rajeev K., et al.
Publicado: (2018)

Repaired coarctation of the aorta, persistent arterial hypertension and the selfish brain
por: Rodrigues, Jonathan C. L., et al.
Publicado: (2019)

Hypertension and cognitive dysfunction in elderly: blood pressure management for this global burden
por: Tadic, Marijana, et al.
Publicado: (2016)

Control of sympathetic vasomotor tone by catecholaminergic C1 neurones of the rostral ventrolateral medulla oblongata
por: Marina, Nephtali, et al.
Publicado: (2011)

An ELISA for the detection of serum antibodies to both transmissible gastroenteritis virus and porcine respiratory coronavirus
por: Paton, D.J., et al.
Publicado: (1991)

Wellbeing, alcohol use and sexual activity in young teenagers: findings from a cross-sectional survey in school children in North West England
por: Phillips-Howard, Penelope A, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_nqlthof4ju91kljv1iuks7ed9m