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Amyloid β Is Not the Major Factor Accounting for Impaired Adult Hippocampal Neurogenesis in Mice Overexpressing Amyloid Precursor Protein

Adult hippocampal neurogenesis was impaired in several Alzheimer's disease models overexpressing mutant human amyloid precursor protein (hAPP). However, the effects of wild-type hAPP on adult neurogenesis and whether the impaired adult hippocampal neurogenesis was caused by amyloid β (Aβ) or AP...

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Detalles Bibliográficos
Autores principales: Pan, Hongyu, Wang, Dongpi, Zhang, Xiaoqin, Zhou, Dongming, Zhang, Heng, Qian, Qi, He, Xiao, Liu, Zhaoling, Liu, Yunjin, Zheng, Tingting, Zhang, Ling, Wang, Mingkai, Sun, Binggui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063569/
https://www.ncbi.nlm.nih.gov/pubmed/27693425
http://dx.doi.org/10.1016/j.stemcr.2016.08.019