Improved Human Erythropoiesis and Platelet Formation in Humanized NSGW41 Mice

Human erythro-megakaryopoiesis does not occur in humanized mouse models, preventing the in vivo analysis of human hematopoietic stem cell (HSC) differentiation into these lineages in a surrogate host. Here we show that stably engrafted KIT-deficient NOD/SCID Il2rg(−/−)Kit(W41/W41) (NSGW41) mice supp...

Descripción completa

Detalles Bibliográficos
Autores principales: Rahmig, Susann, Kronstein-Wiedemann, Romy, Fohgrub, Juliane, Kronstein, Nicole, Nevmerzhitskaya, Aleksandra, Bornhäuser, Martin, Gassmann, Max, Platz, Alexander, Ordemann, Rainer, Tonn, Torsten, Waskow, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063583/
https://www.ncbi.nlm.nih.gov/pubmed/27618723
http://dx.doi.org/10.1016/j.stemcr.2016.08.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063583/
https://www.ncbi.nlm.nih.gov/pubmed/27618723
http://dx.doi.org/10.1016/j.stemcr.2016.08.005

Ejemplares similares