Thrombospondin expression in myofibers stabilizes muscle membranes

Skeletal muscle is highly sensitive to mutations in genes that participate in membrane stability and cellular attachment, which often leads to muscular dystrophy. Here we show that Thrombospondin-4 (Thbs4) regulates skeletal muscle integrity and its susceptibility to muscular dystrophy through organ...

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Detalles Bibliográficos
Autores principales: Vanhoutte, Davy, Schips, Tobias G, Kwong, Jennifer Q, Davis, Jennifer, Tjondrokoesoemo, Andoria, Brody, Matthew J, Sargent, Michelle A, Kanisicak, Onur, Yi, Hong, Gao, Quan Q, Rabinowitz, Joseph E, Volk, Talila, McNally, Elizabeth M, Molkentin, Jeffery D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063588/
https://www.ncbi.nlm.nih.gov/pubmed/27669143
http://dx.doi.org/10.7554/eLife.17589

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