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Moringin activates Wnt canonical pathway by inhibiting GSK3β in a mouse model of experimental autoimmune encephalomyelitis

Aberrant canonical Wnt–β-catenin signaling has been reported in multiple sclerosis (MS), although the results are controversial. The present study aimed to examine the role of the Wnt–β-catenin pathway in experimental MS and also to test moringin (4-[α-L-rhamnopyranosyloxy]-benzyl isothiocyanate), r...

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Detalles Bibliográficos
Autores principales:	Giacoppo, Sabrina, Soundara Rajan, Thangavelu, De Nicola, Gina Rosalinda, Iori, Renato, Bramanti, Placido, Mazzon, Emanuela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063603/ https://www.ncbi.nlm.nih.gov/pubmed/27784989 http://dx.doi.org/10.2147/DDDT.S110514

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