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Biokinetic datasets of PEI F25-LMW complexed and non-complexed (32)P-siRNA within different lung compartments

Biokinetics data of lung-administered PEI F25-LMW/siRNA polyplexes within different lung compartments are presented. Thereby, at three different timepoints (1 h, 3 h, 8 h), the data was determined by calculations to the (32)P-radioactivity in the whole mouse body. Additionally, data was optimized to...

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Detalles Bibliográficos
Autores principales: Lipka, Jens, Semmler-Behnke, Manuela, Wenk, Alexander, Burkhardt, Jana, Aigner, Achim, Kreyling, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063804/
https://www.ncbi.nlm.nih.gov/pubmed/27761500
http://dx.doi.org/10.1016/j.dib.2016.03.092
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author Lipka, Jens
Semmler-Behnke, Manuela
Wenk, Alexander
Burkhardt, Jana
Aigner, Achim
Kreyling, Wolfgang
author_facet Lipka, Jens
Semmler-Behnke, Manuela
Wenk, Alexander
Burkhardt, Jana
Aigner, Achim
Kreyling, Wolfgang
author_sort Lipka, Jens
collection PubMed
description Biokinetics data of lung-administered PEI F25-LMW/siRNA polyplexes within different lung compartments are presented. Thereby, at three different timepoints (1 h, 3 h, 8 h), the data was determined by calculations to the (32)P-radioactivity in the whole mouse body. Additionally, data was optimized to the available PEI F25-LMW/siRNA polyplexes in the target organ and therefore normalized to the sum of all lung compartments. Methods, other biokinetics data and the discussion of the results are published in “Biokinetic studies of non-complexed siRNA versus nano-sized PEI F25-LMW/siRNA polyplexes following intratracheal instillation into mice” (Lipka et al., 2016 [1]).
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spelling pubmed-50638042016-10-19 Biokinetic datasets of PEI F25-LMW complexed and non-complexed (32)P-siRNA within different lung compartments Lipka, Jens Semmler-Behnke, Manuela Wenk, Alexander Burkhardt, Jana Aigner, Achim Kreyling, Wolfgang Data Brief Data Article Biokinetics data of lung-administered PEI F25-LMW/siRNA polyplexes within different lung compartments are presented. Thereby, at three different timepoints (1 h, 3 h, 8 h), the data was determined by calculations to the (32)P-radioactivity in the whole mouse body. Additionally, data was optimized to the available PEI F25-LMW/siRNA polyplexes in the target organ and therefore normalized to the sum of all lung compartments. Methods, other biokinetics data and the discussion of the results are published in “Biokinetic studies of non-complexed siRNA versus nano-sized PEI F25-LMW/siRNA polyplexes following intratracheal instillation into mice” (Lipka et al., 2016 [1]). Elsevier 2016-04-01 /pmc/articles/PMC5063804/ /pubmed/27761500 http://dx.doi.org/10.1016/j.dib.2016.03.092 Text en © 2016 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Data Article
Lipka, Jens
Semmler-Behnke, Manuela
Wenk, Alexander
Burkhardt, Jana
Aigner, Achim
Kreyling, Wolfgang
Biokinetic datasets of PEI F25-LMW complexed and non-complexed (32)P-siRNA within different lung compartments
title Biokinetic datasets of PEI F25-LMW complexed and non-complexed (32)P-siRNA within different lung compartments
title_full Biokinetic datasets of PEI F25-LMW complexed and non-complexed (32)P-siRNA within different lung compartments
title_fullStr Biokinetic datasets of PEI F25-LMW complexed and non-complexed (32)P-siRNA within different lung compartments
title_full_unstemmed Biokinetic datasets of PEI F25-LMW complexed and non-complexed (32)P-siRNA within different lung compartments
title_short Biokinetic datasets of PEI F25-LMW complexed and non-complexed (32)P-siRNA within different lung compartments
title_sort biokinetic datasets of pei f25-lmw complexed and non-complexed (32)p-sirna within different lung compartments
topic Data Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063804/
https://www.ncbi.nlm.nih.gov/pubmed/27761500
http://dx.doi.org/10.1016/j.dib.2016.03.092
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