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Biokinetic datasets of PEI F25-LMW complexed and non-complexed (32)P-siRNA within different lung compartments
Biokinetics data of lung-administered PEI F25-LMW/siRNA polyplexes within different lung compartments are presented. Thereby, at three different timepoints (1 h, 3 h, 8 h), the data was determined by calculations to the (32)P-radioactivity in the whole mouse body. Additionally, data was optimized to...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063804/ https://www.ncbi.nlm.nih.gov/pubmed/27761500 http://dx.doi.org/10.1016/j.dib.2016.03.092 |
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author | Lipka, Jens Semmler-Behnke, Manuela Wenk, Alexander Burkhardt, Jana Aigner, Achim Kreyling, Wolfgang |
author_facet | Lipka, Jens Semmler-Behnke, Manuela Wenk, Alexander Burkhardt, Jana Aigner, Achim Kreyling, Wolfgang |
author_sort | Lipka, Jens |
collection | PubMed |
description | Biokinetics data of lung-administered PEI F25-LMW/siRNA polyplexes within different lung compartments are presented. Thereby, at three different timepoints (1 h, 3 h, 8 h), the data was determined by calculations to the (32)P-radioactivity in the whole mouse body. Additionally, data was optimized to the available PEI F25-LMW/siRNA polyplexes in the target organ and therefore normalized to the sum of all lung compartments. Methods, other biokinetics data and the discussion of the results are published in “Biokinetic studies of non-complexed siRNA versus nano-sized PEI F25-LMW/siRNA polyplexes following intratracheal instillation into mice” (Lipka et al., 2016 [1]). |
format | Online Article Text |
id | pubmed-5063804 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-50638042016-10-19 Biokinetic datasets of PEI F25-LMW complexed and non-complexed (32)P-siRNA within different lung compartments Lipka, Jens Semmler-Behnke, Manuela Wenk, Alexander Burkhardt, Jana Aigner, Achim Kreyling, Wolfgang Data Brief Data Article Biokinetics data of lung-administered PEI F25-LMW/siRNA polyplexes within different lung compartments are presented. Thereby, at three different timepoints (1 h, 3 h, 8 h), the data was determined by calculations to the (32)P-radioactivity in the whole mouse body. Additionally, data was optimized to the available PEI F25-LMW/siRNA polyplexes in the target organ and therefore normalized to the sum of all lung compartments. Methods, other biokinetics data and the discussion of the results are published in “Biokinetic studies of non-complexed siRNA versus nano-sized PEI F25-LMW/siRNA polyplexes following intratracheal instillation into mice” (Lipka et al., 2016 [1]). Elsevier 2016-04-01 /pmc/articles/PMC5063804/ /pubmed/27761500 http://dx.doi.org/10.1016/j.dib.2016.03.092 Text en © 2016 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Data Article Lipka, Jens Semmler-Behnke, Manuela Wenk, Alexander Burkhardt, Jana Aigner, Achim Kreyling, Wolfgang Biokinetic datasets of PEI F25-LMW complexed and non-complexed (32)P-siRNA within different lung compartments |
title | Biokinetic datasets of PEI F25-LMW complexed and non-complexed (32)P-siRNA within different lung compartments |
title_full | Biokinetic datasets of PEI F25-LMW complexed and non-complexed (32)P-siRNA within different lung compartments |
title_fullStr | Biokinetic datasets of PEI F25-LMW complexed and non-complexed (32)P-siRNA within different lung compartments |
title_full_unstemmed | Biokinetic datasets of PEI F25-LMW complexed and non-complexed (32)P-siRNA within different lung compartments |
title_short | Biokinetic datasets of PEI F25-LMW complexed and non-complexed (32)P-siRNA within different lung compartments |
title_sort | biokinetic datasets of pei f25-lmw complexed and non-complexed (32)p-sirna within different lung compartments |
topic | Data Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063804/ https://www.ncbi.nlm.nih.gov/pubmed/27761500 http://dx.doi.org/10.1016/j.dib.2016.03.092 |
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