Cargando…
Data on the potential impact of food supplements on the growth of mouse embryonic stem cells
The use of new compounds as dietary supplements is increasing, but little is known in terms of possible consequences of their use. Pluripotent stem cells are a promising research tool for citotoxicological research for evaluation of proliferation, cell death, pluripotency and differentiation. Using...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063814/ https://www.ncbi.nlm.nih.gov/pubmed/27761502 http://dx.doi.org/10.1016/j.dib.2016.03.098 |
_version_ | 1782460035497984000 |
---|---|
author | Correia, Marcelo Sousa, Maria I. Rodrigues, Ana S. Perestrelo, Tânia Pereira, Sandro L. Ribeiro, Marcelo F. Ramalho-Santos, João |
author_facet | Correia, Marcelo Sousa, Maria I. Rodrigues, Ana S. Perestrelo, Tânia Pereira, Sandro L. Ribeiro, Marcelo F. Ramalho-Santos, João |
author_sort | Correia, Marcelo |
collection | PubMed |
description | The use of new compounds as dietary supplements is increasing, but little is known in terms of possible consequences of their use. Pluripotent stem cells are a promising research tool for citotoxicological research for evaluation of proliferation, cell death, pluripotency and differentiation. Using the mouse embryonic stem cell (mESC) model, we present data on three different compounds that have been proposed as new potential supplements for co-adjuvant disease treatments: kaempferol, berberine and Tauroursodeoxycholic acid (TUDCA). Cell number and viability were monitored following treatment with increased concentrations of each drug in pluripotent culture conditions. |
format | Online Article Text |
id | pubmed-5063814 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-50638142016-10-19 Data on the potential impact of food supplements on the growth of mouse embryonic stem cells Correia, Marcelo Sousa, Maria I. Rodrigues, Ana S. Perestrelo, Tânia Pereira, Sandro L. Ribeiro, Marcelo F. Ramalho-Santos, João Data Brief Data Article The use of new compounds as dietary supplements is increasing, but little is known in terms of possible consequences of their use. Pluripotent stem cells are a promising research tool for citotoxicological research for evaluation of proliferation, cell death, pluripotency and differentiation. Using the mouse embryonic stem cell (mESC) model, we present data on three different compounds that have been proposed as new potential supplements for co-adjuvant disease treatments: kaempferol, berberine and Tauroursodeoxycholic acid (TUDCA). Cell number and viability were monitored following treatment with increased concentrations of each drug in pluripotent culture conditions. Elsevier 2016-04-04 /pmc/articles/PMC5063814/ /pubmed/27761502 http://dx.doi.org/10.1016/j.dib.2016.03.098 Text en © 2016 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Data Article Correia, Marcelo Sousa, Maria I. Rodrigues, Ana S. Perestrelo, Tânia Pereira, Sandro L. Ribeiro, Marcelo F. Ramalho-Santos, João Data on the potential impact of food supplements on the growth of mouse embryonic stem cells |
title | Data on the potential impact of food supplements on the growth of mouse embryonic stem cells |
title_full | Data on the potential impact of food supplements on the growth of mouse embryonic stem cells |
title_fullStr | Data on the potential impact of food supplements on the growth of mouse embryonic stem cells |
title_full_unstemmed | Data on the potential impact of food supplements on the growth of mouse embryonic stem cells |
title_short | Data on the potential impact of food supplements on the growth of mouse embryonic stem cells |
title_sort | data on the potential impact of food supplements on the growth of mouse embryonic stem cells |
topic | Data Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063814/ https://www.ncbi.nlm.nih.gov/pubmed/27761502 http://dx.doi.org/10.1016/j.dib.2016.03.098 |
work_keys_str_mv | AT correiamarcelo dataonthepotentialimpactoffoodsupplementsonthegrowthofmouseembryonicstemcells AT sousamariai dataonthepotentialimpactoffoodsupplementsonthegrowthofmouseembryonicstemcells AT rodriguesanas dataonthepotentialimpactoffoodsupplementsonthegrowthofmouseembryonicstemcells AT perestrelotania dataonthepotentialimpactoffoodsupplementsonthegrowthofmouseembryonicstemcells AT pereirasandrol dataonthepotentialimpactoffoodsupplementsonthegrowthofmouseembryonicstemcells AT ribeiromarcelof dataonthepotentialimpactoffoodsupplementsonthegrowthofmouseembryonicstemcells AT ramalhosantosjoao dataonthepotentialimpactoffoodsupplementsonthegrowthofmouseembryonicstemcells |