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Data on the potential impact of food supplements on the growth of mouse embryonic stem cells

The use of new compounds as dietary supplements is increasing, but little is known in terms of possible consequences of their use. Pluripotent stem cells are a promising research tool for citotoxicological research for evaluation of proliferation, cell death, pluripotency and differentiation. Using...

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Autores principales: Correia, Marcelo, Sousa, Maria I., Rodrigues, Ana S., Perestrelo, Tânia, Pereira, Sandro L., Ribeiro, Marcelo F., Ramalho-Santos, João
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063814/
https://www.ncbi.nlm.nih.gov/pubmed/27761502
http://dx.doi.org/10.1016/j.dib.2016.03.098
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author Correia, Marcelo
Sousa, Maria I.
Rodrigues, Ana S.
Perestrelo, Tânia
Pereira, Sandro L.
Ribeiro, Marcelo F.
Ramalho-Santos, João
author_facet Correia, Marcelo
Sousa, Maria I.
Rodrigues, Ana S.
Perestrelo, Tânia
Pereira, Sandro L.
Ribeiro, Marcelo F.
Ramalho-Santos, João
author_sort Correia, Marcelo
collection PubMed
description The use of new compounds as dietary supplements is increasing, but little is known in terms of possible consequences of their use. Pluripotent stem cells are a promising research tool for citotoxicological research for evaluation of proliferation, cell death, pluripotency and differentiation. Using the mouse embryonic stem cell (mESC) model, we present data on three different compounds that have been proposed as new potential supplements for co-adjuvant disease treatments: kaempferol, berberine and Tauroursodeoxycholic acid (TUDCA). Cell number and viability were monitored following treatment with increased concentrations of each drug in pluripotent culture conditions.
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spelling pubmed-50638142016-10-19 Data on the potential impact of food supplements on the growth of mouse embryonic stem cells Correia, Marcelo Sousa, Maria I. Rodrigues, Ana S. Perestrelo, Tânia Pereira, Sandro L. Ribeiro, Marcelo F. Ramalho-Santos, João Data Brief Data Article The use of new compounds as dietary supplements is increasing, but little is known in terms of possible consequences of their use. Pluripotent stem cells are a promising research tool for citotoxicological research for evaluation of proliferation, cell death, pluripotency and differentiation. Using the mouse embryonic stem cell (mESC) model, we present data on three different compounds that have been proposed as new potential supplements for co-adjuvant disease treatments: kaempferol, berberine and Tauroursodeoxycholic acid (TUDCA). Cell number and viability were monitored following treatment with increased concentrations of each drug in pluripotent culture conditions. Elsevier 2016-04-04 /pmc/articles/PMC5063814/ /pubmed/27761502 http://dx.doi.org/10.1016/j.dib.2016.03.098 Text en © 2016 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Data Article
Correia, Marcelo
Sousa, Maria I.
Rodrigues, Ana S.
Perestrelo, Tânia
Pereira, Sandro L.
Ribeiro, Marcelo F.
Ramalho-Santos, João
Data on the potential impact of food supplements on the growth of mouse embryonic stem cells
title Data on the potential impact of food supplements on the growth of mouse embryonic stem cells
title_full Data on the potential impact of food supplements on the growth of mouse embryonic stem cells
title_fullStr Data on the potential impact of food supplements on the growth of mouse embryonic stem cells
title_full_unstemmed Data on the potential impact of food supplements on the growth of mouse embryonic stem cells
title_short Data on the potential impact of food supplements on the growth of mouse embryonic stem cells
title_sort data on the potential impact of food supplements on the growth of mouse embryonic stem cells
topic Data Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063814/
https://www.ncbi.nlm.nih.gov/pubmed/27761502
http://dx.doi.org/10.1016/j.dib.2016.03.098
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