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PYY-Dependent Restoration of Impaired Insulin and Glucagon Secretion in Type 2 Diabetes following Roux-En-Y Gastric Bypass Surgery
Roux-en-Y gastric bypass (RYGB) is a weight-reduction procedure resulting in rapid resolution of type 2 diabetes (T2D). The role of pancreatic islet function in this restoration of normoglycemia has not been fully elucidated. Using the diabetic Goto-Kakizaki (GK) rat model, we demonstrate that RYGB...
Autores principales: | Ramracheya, Reshma D., McCulloch, Laura J., Clark, Anne, Wiggins, David, Johannessen, Helene, Olsen, Magnus Kringstad, Cai, Xing, Zhao, Chun-Mei, Chen, Duan, Rorsman, Patrik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063952/ https://www.ncbi.nlm.nih.gov/pubmed/27117413 http://dx.doi.org/10.1016/j.celrep.2016.03.091 |
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