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Prolonged feeding with guanidinoacetate, a methyl group consumer, exacerbates ethanol-induced liver injury

AIM: To investigate the hypothesis that exposure to guanidinoacetate (GAA, a potent methyl-group consumer) either alone or combined with ethanol intake for a prolonged period of time would cause more advanced liver pathology thus identifying methylation defects as the initiator and stimulator for pr...

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Detalles Bibliográficos
Autores principales: Osna, Natalia A, Feng, Dan, Ganesan, Murali, Maillacheruvu, Priya F, Orlicky, David J, French, Samuel W, Tuma, Dean J, Kharbanda, Kusum K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064031/
https://www.ncbi.nlm.nih.gov/pubmed/27784962
http://dx.doi.org/10.3748/wjg.v22.i38.8497

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