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GASTRIC AND JEJUNAL HISTOPATHOLOGICAL CHANGES IN PATIENTS UNDERGOING BARIATRIC SURGERY

BACKGROUND: Morbid obesity is a multifactorial disease that increasingly is being treated by surgery. AIM: To evaluate gastric histopathological changes in obese, and to compare with patients who underwent gastrojejunal bypass and the jejunal mucosa after the surgery. METHODS: This is an observation...

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Autores principales: RODRIGUES, Rosemary Simões Nomelini, ALMEIDA, Élia Cláudia de Souza, CAMILO, Silvia Maria Perrone, TERRA-JÚNIOR, Júverson Alves, GUIMARÃES, Lucinda Calheiros, DUQUE, Ana Cristina da Rocha, ETCHEBEHERE, Renata Margarida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Colégio Brasileiro de Cirurgia Digestiva 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064251/
https://www.ncbi.nlm.nih.gov/pubmed/27683773
http://dx.doi.org/10.1590/0102-6720201600S10010
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author RODRIGUES, Rosemary Simões Nomelini
ALMEIDA, Élia Cláudia de Souza
CAMILO, Silvia Maria Perrone
TERRA-JÚNIOR, Júverson Alves
GUIMARÃES, Lucinda Calheiros
DUQUE, Ana Cristina da Rocha
ETCHEBEHERE, Renata Margarida
author_facet RODRIGUES, Rosemary Simões Nomelini
ALMEIDA, Élia Cláudia de Souza
CAMILO, Silvia Maria Perrone
TERRA-JÚNIOR, Júverson Alves
GUIMARÃES, Lucinda Calheiros
DUQUE, Ana Cristina da Rocha
ETCHEBEHERE, Renata Margarida
author_sort RODRIGUES, Rosemary Simões Nomelini
collection PubMed
description BACKGROUND: Morbid obesity is a multifactorial disease that increasingly is being treated by surgery. AIM: To evaluate gastric histopathological changes in obese, and to compare with patients who underwent gastrojejunal bypass and the jejunal mucosa after the surgery. METHODS: This is an observational study performed at a tertiary public hospital, evaluating endoscopic biopsies from 36 preoperative patients and 35 postoperative. RESULTS: In the preoperative group, 80.6% had chronic gastritis, which was active in 38.9% (77.1% and 20.1%, respectively, in the postoperative). The postoperative group had a significant reduction in H. pylori infection (p=0.0001). A longer length of the gastric stump and a time since surgery of more than two years were associated with Helicobacter pylori infection. The jejunal mucosa was normal in 91.4% and showed slight nonspecific chronic inflammation in 8.6%. CONCLUSION: There was a reduction in the incidence of Helicobacter pylori infection in the postoperative group. A longer length of the gastric stump and longer time elapsed since surgery were associated with Helicobacter pylori infection. The jejunal mucosa was considered normal in an absolute majority of patients.
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spelling pubmed-50642512016-10-18 GASTRIC AND JEJUNAL HISTOPATHOLOGICAL CHANGES IN PATIENTS UNDERGOING BARIATRIC SURGERY RODRIGUES, Rosemary Simões Nomelini ALMEIDA, Élia Cláudia de Souza CAMILO, Silvia Maria Perrone TERRA-JÚNIOR, Júverson Alves GUIMARÃES, Lucinda Calheiros DUQUE, Ana Cristina da Rocha ETCHEBEHERE, Renata Margarida Arq Bras Cir Dig Original Article BACKGROUND: Morbid obesity is a multifactorial disease that increasingly is being treated by surgery. AIM: To evaluate gastric histopathological changes in obese, and to compare with patients who underwent gastrojejunal bypass and the jejunal mucosa after the surgery. METHODS: This is an observational study performed at a tertiary public hospital, evaluating endoscopic biopsies from 36 preoperative patients and 35 postoperative. RESULTS: In the preoperative group, 80.6% had chronic gastritis, which was active in 38.9% (77.1% and 20.1%, respectively, in the postoperative). The postoperative group had a significant reduction in H. pylori infection (p=0.0001). A longer length of the gastric stump and a time since surgery of more than two years were associated with Helicobacter pylori infection. The jejunal mucosa was normal in 91.4% and showed slight nonspecific chronic inflammation in 8.6%. CONCLUSION: There was a reduction in the incidence of Helicobacter pylori infection in the postoperative group. A longer length of the gastric stump and longer time elapsed since surgery were associated with Helicobacter pylori infection. The jejunal mucosa was considered normal in an absolute majority of patients. Colégio Brasileiro de Cirurgia Digestiva 2016 /pmc/articles/PMC5064251/ /pubmed/27683773 http://dx.doi.org/10.1590/0102-6720201600S10010 Text en http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Original Article
RODRIGUES, Rosemary Simões Nomelini
ALMEIDA, Élia Cláudia de Souza
CAMILO, Silvia Maria Perrone
TERRA-JÚNIOR, Júverson Alves
GUIMARÃES, Lucinda Calheiros
DUQUE, Ana Cristina da Rocha
ETCHEBEHERE, Renata Margarida
GASTRIC AND JEJUNAL HISTOPATHOLOGICAL CHANGES IN PATIENTS UNDERGOING BARIATRIC SURGERY
title GASTRIC AND JEJUNAL HISTOPATHOLOGICAL CHANGES IN PATIENTS UNDERGOING BARIATRIC SURGERY
title_full GASTRIC AND JEJUNAL HISTOPATHOLOGICAL CHANGES IN PATIENTS UNDERGOING BARIATRIC SURGERY
title_fullStr GASTRIC AND JEJUNAL HISTOPATHOLOGICAL CHANGES IN PATIENTS UNDERGOING BARIATRIC SURGERY
title_full_unstemmed GASTRIC AND JEJUNAL HISTOPATHOLOGICAL CHANGES IN PATIENTS UNDERGOING BARIATRIC SURGERY
title_short GASTRIC AND JEJUNAL HISTOPATHOLOGICAL CHANGES IN PATIENTS UNDERGOING BARIATRIC SURGERY
title_sort gastric and jejunal histopathological changes in patients undergoing bariatric surgery
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064251/
https://www.ncbi.nlm.nih.gov/pubmed/27683773
http://dx.doi.org/10.1590/0102-6720201600S10010
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