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GASTRIC AND JEJUNAL HISTOPATHOLOGICAL CHANGES IN PATIENTS UNDERGOING BARIATRIC SURGERY
BACKGROUND: Morbid obesity is a multifactorial disease that increasingly is being treated by surgery. AIM: To evaluate gastric histopathological changes in obese, and to compare with patients who underwent gastrojejunal bypass and the jejunal mucosa after the surgery. METHODS: This is an observation...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Colégio Brasileiro de Cirurgia Digestiva
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064251/ https://www.ncbi.nlm.nih.gov/pubmed/27683773 http://dx.doi.org/10.1590/0102-6720201600S10010 |
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author | RODRIGUES, Rosemary Simões Nomelini ALMEIDA, Élia Cláudia de Souza CAMILO, Silvia Maria Perrone TERRA-JÚNIOR, Júverson Alves GUIMARÃES, Lucinda Calheiros DUQUE, Ana Cristina da Rocha ETCHEBEHERE, Renata Margarida |
author_facet | RODRIGUES, Rosemary Simões Nomelini ALMEIDA, Élia Cláudia de Souza CAMILO, Silvia Maria Perrone TERRA-JÚNIOR, Júverson Alves GUIMARÃES, Lucinda Calheiros DUQUE, Ana Cristina da Rocha ETCHEBEHERE, Renata Margarida |
author_sort | RODRIGUES, Rosemary Simões Nomelini |
collection | PubMed |
description | BACKGROUND: Morbid obesity is a multifactorial disease that increasingly is being treated by surgery. AIM: To evaluate gastric histopathological changes in obese, and to compare with patients who underwent gastrojejunal bypass and the jejunal mucosa after the surgery. METHODS: This is an observational study performed at a tertiary public hospital, evaluating endoscopic biopsies from 36 preoperative patients and 35 postoperative. RESULTS: In the preoperative group, 80.6% had chronic gastritis, which was active in 38.9% (77.1% and 20.1%, respectively, in the postoperative). The postoperative group had a significant reduction in H. pylori infection (p=0.0001). A longer length of the gastric stump and a time since surgery of more than two years were associated with Helicobacter pylori infection. The jejunal mucosa was normal in 91.4% and showed slight nonspecific chronic inflammation in 8.6%. CONCLUSION: There was a reduction in the incidence of Helicobacter pylori infection in the postoperative group. A longer length of the gastric stump and longer time elapsed since surgery were associated with Helicobacter pylori infection. The jejunal mucosa was considered normal in an absolute majority of patients. |
format | Online Article Text |
id | pubmed-5064251 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Colégio Brasileiro de Cirurgia Digestiva |
record_format | MEDLINE/PubMed |
spelling | pubmed-50642512016-10-18 GASTRIC AND JEJUNAL HISTOPATHOLOGICAL CHANGES IN PATIENTS UNDERGOING BARIATRIC SURGERY RODRIGUES, Rosemary Simões Nomelini ALMEIDA, Élia Cláudia de Souza CAMILO, Silvia Maria Perrone TERRA-JÚNIOR, Júverson Alves GUIMARÃES, Lucinda Calheiros DUQUE, Ana Cristina da Rocha ETCHEBEHERE, Renata Margarida Arq Bras Cir Dig Original Article BACKGROUND: Morbid obesity is a multifactorial disease that increasingly is being treated by surgery. AIM: To evaluate gastric histopathological changes in obese, and to compare with patients who underwent gastrojejunal bypass and the jejunal mucosa after the surgery. METHODS: This is an observational study performed at a tertiary public hospital, evaluating endoscopic biopsies from 36 preoperative patients and 35 postoperative. RESULTS: In the preoperative group, 80.6% had chronic gastritis, which was active in 38.9% (77.1% and 20.1%, respectively, in the postoperative). The postoperative group had a significant reduction in H. pylori infection (p=0.0001). A longer length of the gastric stump and a time since surgery of more than two years were associated with Helicobacter pylori infection. The jejunal mucosa was normal in 91.4% and showed slight nonspecific chronic inflammation in 8.6%. CONCLUSION: There was a reduction in the incidence of Helicobacter pylori infection in the postoperative group. A longer length of the gastric stump and longer time elapsed since surgery were associated with Helicobacter pylori infection. The jejunal mucosa was considered normal in an absolute majority of patients. Colégio Brasileiro de Cirurgia Digestiva 2016 /pmc/articles/PMC5064251/ /pubmed/27683773 http://dx.doi.org/10.1590/0102-6720201600S10010 Text en http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License |
spellingShingle | Original Article RODRIGUES, Rosemary Simões Nomelini ALMEIDA, Élia Cláudia de Souza CAMILO, Silvia Maria Perrone TERRA-JÚNIOR, Júverson Alves GUIMARÃES, Lucinda Calheiros DUQUE, Ana Cristina da Rocha ETCHEBEHERE, Renata Margarida GASTRIC AND JEJUNAL HISTOPATHOLOGICAL CHANGES IN PATIENTS UNDERGOING BARIATRIC SURGERY |
title | GASTRIC AND JEJUNAL HISTOPATHOLOGICAL CHANGES IN PATIENTS UNDERGOING
BARIATRIC SURGERY |
title_full | GASTRIC AND JEJUNAL HISTOPATHOLOGICAL CHANGES IN PATIENTS UNDERGOING
BARIATRIC SURGERY |
title_fullStr | GASTRIC AND JEJUNAL HISTOPATHOLOGICAL CHANGES IN PATIENTS UNDERGOING
BARIATRIC SURGERY |
title_full_unstemmed | GASTRIC AND JEJUNAL HISTOPATHOLOGICAL CHANGES IN PATIENTS UNDERGOING
BARIATRIC SURGERY |
title_short | GASTRIC AND JEJUNAL HISTOPATHOLOGICAL CHANGES IN PATIENTS UNDERGOING
BARIATRIC SURGERY |
title_sort | gastric and jejunal histopathological changes in patients undergoing
bariatric surgery |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064251/ https://www.ncbi.nlm.nih.gov/pubmed/27683773 http://dx.doi.org/10.1590/0102-6720201600S10010 |
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