Locally Advanced Stage High-Grade Mucoepidermoid Carcinoma of Salivary Gland in a 9-Year-Old Girl: The Controversy of Adjuvant Therapy

Malignant salivary gland tumors are rare in children, mostly represented by low-grade mucoepidermoid carcinomas. For these patients, long-term survival rates above 95% are reported after surgical resection. Here we report a case of a 9-year-old girl with a high grade locally advanced mucoepidermoid...

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Autores principales: Martínez, Olga Micol, Dorado, Elena Daghoum, García, María Dolores Amorós, Ramírez, María Isabel Oviedo, de la Fuente Muñoz, Isabel, Soler, Jose Luis Fuster
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064301/
https://www.ncbi.nlm.nih.gov/pubmed/27746885
http://dx.doi.org/10.4081/rt.2016.6429
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author Martínez, Olga Micol
Dorado, Elena Daghoum
García, María Dolores Amorós
Ramírez, María Isabel Oviedo
de la Fuente Muñoz, Isabel
Soler, Jose Luis Fuster
author_facet Martínez, Olga Micol
Dorado, Elena Daghoum
García, María Dolores Amorós
Ramírez, María Isabel Oviedo
de la Fuente Muñoz, Isabel
Soler, Jose Luis Fuster
author_sort Martínez, Olga Micol
collection PubMed
description Malignant salivary gland tumors are rare in children, mostly represented by low-grade mucoepidermoid carcinomas. For these patients, long-term survival rates above 95% are reported after surgical resection. Here we report a case of a 9-year-old girl with a high grade locally advanced mucoepidermoid carcinoma undergoing adjuvant radiotherapy and chemotherapy after surgery. We emphasize the controversy and lack of evidence-based indication for these highly toxic adjuvant therapy modalities in children.
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spelling pubmed-50643012016-10-14 Locally Advanced Stage High-Grade Mucoepidermoid Carcinoma of Salivary Gland in a 9-Year-Old Girl: The Controversy of Adjuvant Therapy Martínez, Olga Micol Dorado, Elena Daghoum García, María Dolores Amorós Ramírez, María Isabel Oviedo de la Fuente Muñoz, Isabel Soler, Jose Luis Fuster Rare Tumors Case Report Malignant salivary gland tumors are rare in children, mostly represented by low-grade mucoepidermoid carcinomas. For these patients, long-term survival rates above 95% are reported after surgical resection. Here we report a case of a 9-year-old girl with a high grade locally advanced mucoepidermoid carcinoma undergoing adjuvant radiotherapy and chemotherapy after surgery. We emphasize the controversy and lack of evidence-based indication for these highly toxic adjuvant therapy modalities in children. PAGEPress Publications, Pavia, Italy 2016-10-06 /pmc/articles/PMC5064301/ /pubmed/27746885 http://dx.doi.org/10.4081/rt.2016.6429 Text en ©Copyright O.M. Martínez et al. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Martínez, Olga Micol
Dorado, Elena Daghoum
García, María Dolores Amorós
Ramírez, María Isabel Oviedo
de la Fuente Muñoz, Isabel
Soler, Jose Luis Fuster
Locally Advanced Stage High-Grade Mucoepidermoid Carcinoma of Salivary Gland in a 9-Year-Old Girl: The Controversy of Adjuvant Therapy
title Locally Advanced Stage High-Grade Mucoepidermoid Carcinoma of Salivary Gland in a 9-Year-Old Girl: The Controversy of Adjuvant Therapy
title_full Locally Advanced Stage High-Grade Mucoepidermoid Carcinoma of Salivary Gland in a 9-Year-Old Girl: The Controversy of Adjuvant Therapy
title_fullStr Locally Advanced Stage High-Grade Mucoepidermoid Carcinoma of Salivary Gland in a 9-Year-Old Girl: The Controversy of Adjuvant Therapy
title_full_unstemmed Locally Advanced Stage High-Grade Mucoepidermoid Carcinoma of Salivary Gland in a 9-Year-Old Girl: The Controversy of Adjuvant Therapy
title_short Locally Advanced Stage High-Grade Mucoepidermoid Carcinoma of Salivary Gland in a 9-Year-Old Girl: The Controversy of Adjuvant Therapy
title_sort locally advanced stage high-grade mucoepidermoid carcinoma of salivary gland in a 9-year-old girl: the controversy of adjuvant therapy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064301/
https://www.ncbi.nlm.nih.gov/pubmed/27746885
http://dx.doi.org/10.4081/rt.2016.6429
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