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Soft Tissue Myoepithelial Carcinoma of the Neck with Spinal Invasion

Soft tissue myoepithelial neoplasms are a rare yet diverse group of tumors, ranging from benign to malignant lesions. Their presentation in the head and neck region is uncommon and represents a challenging diagnosis. Early identification of myoepithelial carcinoma is crucial given its more aggressiv...

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Autores principales: Moussaly, Elias, Nazha, Bassel, Kedia, Shiksha, Chang, Qing, Forte, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064303/
https://www.ncbi.nlm.nih.gov/pubmed/27746887
http://dx.doi.org/10.4081/rt.2016.6485
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author Moussaly, Elias
Nazha, Bassel
Kedia, Shiksha
Chang, Qing
Forte, Frank
author_facet Moussaly, Elias
Nazha, Bassel
Kedia, Shiksha
Chang, Qing
Forte, Frank
author_sort Moussaly, Elias
collection PubMed
description Soft tissue myoepithelial neoplasms are a rare yet diverse group of tumors, ranging from benign to malignant lesions. Their presentation in the head and neck region is uncommon and represents a challenging diagnosis. Early identification of myoepithelial carcinoma is crucial given its more aggressive course compared to its benign counterpart, although the histopathological distinction between the two can be difficult. EWSR1 gene rearrangement is found in half the cases and has a speculative role in pathogenesis. Complete excision remains the treatment of choice. The roles of chemotherapy and radiation are unclear. We report the hospital course of a 33-year-old female who presented to our institution with a posterior neck mass with spinal invasion, diagnosed as myoepithelial cancer. A literature review of these rare tumors is discussed here.
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spelling pubmed-50643032016-10-14 Soft Tissue Myoepithelial Carcinoma of the Neck with Spinal Invasion Moussaly, Elias Nazha, Bassel Kedia, Shiksha Chang, Qing Forte, Frank Rare Tumors Case Report Soft tissue myoepithelial neoplasms are a rare yet diverse group of tumors, ranging from benign to malignant lesions. Their presentation in the head and neck region is uncommon and represents a challenging diagnosis. Early identification of myoepithelial carcinoma is crucial given its more aggressive course compared to its benign counterpart, although the histopathological distinction between the two can be difficult. EWSR1 gene rearrangement is found in half the cases and has a speculative role in pathogenesis. Complete excision remains the treatment of choice. The roles of chemotherapy and radiation are unclear. We report the hospital course of a 33-year-old female who presented to our institution with a posterior neck mass with spinal invasion, diagnosed as myoepithelial cancer. A literature review of these rare tumors is discussed here. PAGEPress Publications, Pavia, Italy 2016-10-06 /pmc/articles/PMC5064303/ /pubmed/27746887 http://dx.doi.org/10.4081/rt.2016.6485 Text en ©Copyright E. Moussaly et al. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Moussaly, Elias
Nazha, Bassel
Kedia, Shiksha
Chang, Qing
Forte, Frank
Soft Tissue Myoepithelial Carcinoma of the Neck with Spinal Invasion
title Soft Tissue Myoepithelial Carcinoma of the Neck with Spinal Invasion
title_full Soft Tissue Myoepithelial Carcinoma of the Neck with Spinal Invasion
title_fullStr Soft Tissue Myoepithelial Carcinoma of the Neck with Spinal Invasion
title_full_unstemmed Soft Tissue Myoepithelial Carcinoma of the Neck with Spinal Invasion
title_short Soft Tissue Myoepithelial Carcinoma of the Neck with Spinal Invasion
title_sort soft tissue myoepithelial carcinoma of the neck with spinal invasion
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064303/
https://www.ncbi.nlm.nih.gov/pubmed/27746887
http://dx.doi.org/10.4081/rt.2016.6485
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