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Soft Tissue Myoepithelial Carcinoma of the Neck with Spinal Invasion
Soft tissue myoepithelial neoplasms are a rare yet diverse group of tumors, ranging from benign to malignant lesions. Their presentation in the head and neck region is uncommon and represents a challenging diagnosis. Early identification of myoepithelial carcinoma is crucial given its more aggressiv...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PAGEPress Publications, Pavia, Italy
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064303/ https://www.ncbi.nlm.nih.gov/pubmed/27746887 http://dx.doi.org/10.4081/rt.2016.6485 |
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author | Moussaly, Elias Nazha, Bassel Kedia, Shiksha Chang, Qing Forte, Frank |
author_facet | Moussaly, Elias Nazha, Bassel Kedia, Shiksha Chang, Qing Forte, Frank |
author_sort | Moussaly, Elias |
collection | PubMed |
description | Soft tissue myoepithelial neoplasms are a rare yet diverse group of tumors, ranging from benign to malignant lesions. Their presentation in the head and neck region is uncommon and represents a challenging diagnosis. Early identification of myoepithelial carcinoma is crucial given its more aggressive course compared to its benign counterpart, although the histopathological distinction between the two can be difficult. EWSR1 gene rearrangement is found in half the cases and has a speculative role in pathogenesis. Complete excision remains the treatment of choice. The roles of chemotherapy and radiation are unclear. We report the hospital course of a 33-year-old female who presented to our institution with a posterior neck mass with spinal invasion, diagnosed as myoepithelial cancer. A literature review of these rare tumors is discussed here. |
format | Online Article Text |
id | pubmed-5064303 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | PAGEPress Publications, Pavia, Italy |
record_format | MEDLINE/PubMed |
spelling | pubmed-50643032016-10-14 Soft Tissue Myoepithelial Carcinoma of the Neck with Spinal Invasion Moussaly, Elias Nazha, Bassel Kedia, Shiksha Chang, Qing Forte, Frank Rare Tumors Case Report Soft tissue myoepithelial neoplasms are a rare yet diverse group of tumors, ranging from benign to malignant lesions. Their presentation in the head and neck region is uncommon and represents a challenging diagnosis. Early identification of myoepithelial carcinoma is crucial given its more aggressive course compared to its benign counterpart, although the histopathological distinction between the two can be difficult. EWSR1 gene rearrangement is found in half the cases and has a speculative role in pathogenesis. Complete excision remains the treatment of choice. The roles of chemotherapy and radiation are unclear. We report the hospital course of a 33-year-old female who presented to our institution with a posterior neck mass with spinal invasion, diagnosed as myoepithelial cancer. A literature review of these rare tumors is discussed here. PAGEPress Publications, Pavia, Italy 2016-10-06 /pmc/articles/PMC5064303/ /pubmed/27746887 http://dx.doi.org/10.4081/rt.2016.6485 Text en ©Copyright E. Moussaly et al. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Moussaly, Elias Nazha, Bassel Kedia, Shiksha Chang, Qing Forte, Frank Soft Tissue Myoepithelial Carcinoma of the Neck with Spinal Invasion |
title | Soft Tissue Myoepithelial Carcinoma of the Neck with Spinal Invasion |
title_full | Soft Tissue Myoepithelial Carcinoma of the Neck with Spinal Invasion |
title_fullStr | Soft Tissue Myoepithelial Carcinoma of the Neck with Spinal Invasion |
title_full_unstemmed | Soft Tissue Myoepithelial Carcinoma of the Neck with Spinal Invasion |
title_short | Soft Tissue Myoepithelial Carcinoma of the Neck with Spinal Invasion |
title_sort | soft tissue myoepithelial carcinoma of the neck with spinal invasion |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064303/ https://www.ncbi.nlm.nih.gov/pubmed/27746887 http://dx.doi.org/10.4081/rt.2016.6485 |
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