Cargando…

A novel IRS-1-associated protein, DGKζ regulates GLUT4 translocation in 3T3-L1 adipocytes

Insulin receptor substrates (IRSs) are major targets of insulin receptor tyrosine kinases. Here we identified diacylglycerol kinase zeta (DGKζ) as an IRS-1-associated protein, and examined roles of DGKζ in glucose transporter 4 (GLUT4) translocation to the plasma membrane. When DGKζ was knocked-down...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, TingYu, Yu, BuChin, Kakino, Mamoru, Fujimoto, Hitoshi, Ando, Yasutoshi, Hakuno, Fumihiko, Takahashi, Shin-Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064357/
https://www.ncbi.nlm.nih.gov/pubmed/27739494
http://dx.doi.org/10.1038/srep35438

Ejemplares similares