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FUS/TLS acts as an aggregation-dependent modifier of polyglutamine disease model mice

FUS/TLS is an RNA/DNA-binding protein associated with neurodegenerative diseases including amyotrophic lateral sclerosis and frontotemporal lobar degeneration. Previously, we found that a prion-like domain in the N-terminus of FUS/TLS mediates co-aggregation between FUS/TLS and mutant huntingtin, th...

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Detalles Bibliográficos
Autores principales:	Kino, Yoshihiro, Washizu, Chika, Kurosawa, Masaru, Yamada, Mizuki, Doi, Hiroshi, Takumi, Toru, Adachi, Hiroaki, Katsuno, Masahisa, Sobue, Gen, Hicks, Geoffrey G., Hattori, Nobutaka, Shimogori, Tomomi, Nukina, Nobuyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064419/ https://www.ncbi.nlm.nih.gov/pubmed/27739513 http://dx.doi.org/10.1038/srep35236

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