Role of Adipose-derived Stem Cells in Fat Grafting and Reconstructive Surgery

Autologous fat grafting is commonly utilised to reconstruct soft tissue defects caused by ageing, trauma, chronic wounds and cancer resection. The benefits of fat grafting are minimal donor site morbidity and ease of availability through liposuction or lipectomy. Nonetheless, survival and longevity...

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Detalles Bibliográficos
Autores principales: Tan, Shaun S, Ng, Zhi Yang, Zhan, Weiqing, Rozen, Warren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
CME Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064678/
https://www.ncbi.nlm.nih.gov/pubmed/27761084
http://dx.doi.org/10.4103/0974-2077.191672
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author Tan, Shaun S
Ng, Zhi Yang
Zhan, Weiqing
Rozen, Warren
author_facet Tan, Shaun S
Ng, Zhi Yang
Zhan, Weiqing
Rozen, Warren
author_sort Tan, Shaun S
collection PubMed
description Autologous fat grafting is commonly utilised to reconstruct soft tissue defects caused by ageing, trauma, chronic wounds and cancer resection. The benefits of fat grafting are minimal donor site morbidity and ease of availability through liposuction or lipectomy. Nonetheless, survival and longevity of fat grafts remain poor post-engraftment. Various methods to enhance fat graft survival are currently under investigation and its stem cell constituents are of particular interest. Cell-assisted lipotransfer refers to the addition of adipose-derived stem cell (ASC) rich component of stromal vascular fraction to lipoaspirate, the results of which have proven promising. This article aims to review the role of ASCs in fat grafting and reconstructive surgery.
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spelling pubmed-50646782016-10-19 Role of Adipose-derived Stem Cells in Fat Grafting and Reconstructive Surgery Tan, Shaun S Ng, Zhi Yang Zhan, Weiqing Rozen, Warren J Cutan Aesthet Surg CME Article Autologous fat grafting is commonly utilised to reconstruct soft tissue defects caused by ageing, trauma, chronic wounds and cancer resection. The benefits of fat grafting are minimal donor site morbidity and ease of availability through liposuction or lipectomy. Nonetheless, survival and longevity of fat grafts remain poor post-engraftment. Various methods to enhance fat graft survival are currently under investigation and its stem cell constituents are of particular interest. Cell-assisted lipotransfer refers to the addition of adipose-derived stem cell (ASC) rich component of stromal vascular fraction to lipoaspirate, the results of which have proven promising. This article aims to review the role of ASCs in fat grafting and reconstructive surgery. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC5064678/ /pubmed/27761084 http://dx.doi.org/10.4103/0974-2077.191672 Text en Copyright: © Journal of Cutaneous and Aesthetic Surgery http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle CME Article
Tan, Shaun S
Ng, Zhi Yang
Zhan, Weiqing
Rozen, Warren
Role of Adipose-derived Stem Cells in Fat Grafting and Reconstructive Surgery
title Role of Adipose-derived Stem Cells in Fat Grafting and Reconstructive Surgery
title_full Role of Adipose-derived Stem Cells in Fat Grafting and Reconstructive Surgery
title_fullStr Role of Adipose-derived Stem Cells in Fat Grafting and Reconstructive Surgery
title_full_unstemmed Role of Adipose-derived Stem Cells in Fat Grafting and Reconstructive Surgery
title_short Role of Adipose-derived Stem Cells in Fat Grafting and Reconstructive Surgery
title_sort role of adipose-derived stem cells in fat grafting and reconstructive surgery
topic CME Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064678/
https://www.ncbi.nlm.nih.gov/pubmed/27761084
http://dx.doi.org/10.4103/0974-2077.191672
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