Absolute bioavailability of evacetrapib in healthy subjects determined by simultaneous administration of oral evacetrapib and intravenous [(13)C(8)]‐evacetrapib as a tracer

This open‐label, single‐period study in healthy subjects estimated evacetrapib absolute bioavailability following simultaneous administration of a 130‐mg evacetrapib oral dose and 4‐h intravenous (IV) infusion of 175 µg [(13)C(8)]‐evacetrapib as a tracer. Plasma samples collected through 168 h were...

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Detalles Bibliográficos
Autores principales: Cannady, Ellen A., Aburub, Aktham, Ward, Chris, Hinds, Chris, Czeskis, Boris, Ruterbories, Kenneth, Suico, Jeffrey G., Royalty, Jane, Ortega, Demetrio, Pack, Brian W., Begum, Syeda L., Annes, William F., Lin, Qun, Small, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Special Issue Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064742/
https://www.ncbi.nlm.nih.gov/pubmed/26639670
http://dx.doi.org/10.1002/jlcr.3358

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