Huntingtin-associated protein 1: Eutherian adaptation from a TRAK-like protein, conserved gene promoter elements, and localization in the human intestine

BACKGROUND: Huntingtin-associated Protein 1 (HAP1) is expressed in neurons and endocrine cells, and is critical for postnatal survival in mice. HAP1 shares a conserved “HAP1_N” domain with TRAfficking Kinesin proteins TRAK1 and TRAK2 (vertebrate), Milton (Drosophila) and T27A3.1 (C. elegans). HAP1,...

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Detalles Bibliográficos
Autores principales: Lumsden, Amanda L., Young, Richard L., Pezos, Nektaria, Keating, Damien J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064798/
https://www.ncbi.nlm.nih.gov/pubmed/27737633
http://dx.doi.org/10.1186/s12862-016-0780-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064798/
https://www.ncbi.nlm.nih.gov/pubmed/27737633
http://dx.doi.org/10.1186/s12862-016-0780-3

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