Phosphatidylinositol-3 kinase-dependent translational regulation of Id1 involves the PPM1G phosphatase

Id1 is a helix-loop-helix transcriptional modulator that increases the aggressiveness of malignant glial neoplasms. Since most glioblastomas (GBMs) show increased phosphatidylinositol-3 kinase (PI-3K) signaling, we sought to determine whether this pathway regulates Id1 expression. Higher basal Id1 e...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Kaiming, Wang, Lanfang, Feng, Wei, Feng, Yue, Shu, Hui-Kuo G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064830/
https://www.ncbi.nlm.nih.gov/pubmed/27065332
http://dx.doi.org/10.1038/onc.2016.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064830/
https://www.ncbi.nlm.nih.gov/pubmed/27065332
http://dx.doi.org/10.1038/onc.2016.115

Ejemplares similares