Cargando…

Phosphatidylinositol-3 kinase-dependent translational regulation of Id1 involves the PPM1G phosphatase

Id1 is a helix-loop-helix transcriptional modulator that increases the aggressiveness of malignant glial neoplasms. Since most glioblastomas (GBMs) show increased phosphatidylinositol-3 kinase (PI-3K) signaling, we sought to determine whether this pathway regulates Id1 expression. Higher basal Id1 e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Kaiming, Wang, Lanfang, Feng, Wei, Feng, Yue, Shu, Hui-Kuo G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064830/ https://www.ncbi.nlm.nih.gov/pubmed/27065332 http://dx.doi.org/10.1038/onc.2016.115

Ejemplares similares

COX-2 overexpression increases malignant potential of human glioma cells through Id1
por: Xu, Kaiming, et al.
Publicado: (2013)

The Protein Phosphatase PPM1G Destabilizes HIF-1α Expression
por: Pyo, Jaehyuk, et al.
Publicado: (2018)

Phosphatidylinositol Kinases and Phosphatases in Entamoeba histolytica
por: Nakada-Tsukui, Kumiko, et al.
Publicado: (2019)

The phosphatase PPM1A controls monocyte-to-macrophage differentiation
por: Smith, Samuel R., et al.
Publicado: (2018)

Structural basis for the specificity of PPM1H phosphatase for Rab GTPases
por: Waschbüsch, Dieter, et al.
Publicado: (2021)

DNA damage signaling induced by the G-quadruplex ligand 12459 is modulated by PPM1D/WIP1 phosphatase
por: Douarre, Céline, et al.
Publicado: (2013)

Metal dependent protein phosphatase PPM family in cardiac health and diseases
por: Gao, Chen, et al.
Publicado: (2021)

Cadmium is a potent inhibitor of PPM phosphatases and targets the M1 binding site
por: Pan, Chang, et al.
Publicado: (2013)

Identification of HN252 as a potent inhibitor of protein phosphatase PPM1B
por: Lu, Zhiyuan, et al.
Publicado: (2020)

Allosteric inhibition of PPM1D serine/threonine phosphatase via an altered conformational state
por: Miller, Peter G., et al.
Publicado: (2022)

The protein phosphatase PPM1A dephosphorylates and activates YAP to govern mammalian intestinal and liver regeneration
por: Zhou, Ruyuan, et al.
Publicado: (2021)

Palmitoylation targets the calcineurin phosphatase to the phosphatidylinositol 4-kinase complex at the plasma membrane
por: Ulengin-Talkish, Idil, et al.
Publicado: (2021)

PPM1G forms a PPP‐type phosphatase holoenzyme with B56δ that maintains adherens junction integrity
por: Kumar, Parveen, et al.
Publicado: (2019)

Protein phosphatase PPM1B inhibits DYRK1A kinase through dephosphorylation of pS258 and reduces toxic tau aggregation
por: Lee, Ye Hyung, et al.
Publicado: (2021)

An Active C-Terminally Truncated Form of Ca(2+)/Calmodulin-Dependent Protein Kinase Phosphatase-N (CaMKP-N/PPM1E)
por: Ishida, Atsuhiko, et al.
Publicado: (2013)

Regulatory imbalance between LRRK2 kinase, PPM1H phosphatase, and ARF6 GTPase disrupts the axonal transport of autophagosomes
por: Dou, Dan, et al.
Publicado: (2023)

Localization of PPM1H phosphatase tunes Parkinson’s disease-linked LRRK2 kinase-mediated Rab GTPase phosphorylation and ciliogenesis
por: Yeshaw, Wondwossen M., et al.
Publicado: (2023)

PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins
por: Berndsen, Kerryn, et al.
Publicado: (2019)

Prognostic and immunological potential of PPM1G in hepatocellular carcinoma
por: Lin, Yi-Ren, et al.
Publicado: (2021)

Prognostic and immunological potential of PPM1G in lung adenocarcinoma
por: Yin, Rongjiang, et al.
Publicado: (2023)

Lipid Droplet Formation Is Regulated by Ser/Thr Phosphatase PPM1D via Dephosphorylation of Perilipin 1
por: Kamada, Rui, et al.
Publicado: (2022)

AMPKα phosphatase Ppm1E upregulation in human gastric cancer is required for cell proliferation
por: Chen, Min-Bin, et al.
Publicado: (2017)

Protein Phosphatase Magnesium Dependent 1A (PPM1A) Plays a Role in the Differentiation and Survival Processes of Nerve Cells
por: Shohat, Meytal, et al.
Publicado: (2012)

Protein Phosphatase Magnesium-Dependent 1δ (PPM1D) mRNA Expression Is a Prognosis Marker for Hepatocellular Carcinoma
por: Li, Guang-Bing, et al.
Publicado: (2013)

De novo synthesis of protein phosphatase 1A, magnesium dependent, alpha isoform (PPM1A) during oocyte maturation
por: Chuderland, Dana, et al.
Publicado: (2012)

Functional interplay between PPM1G and the transcription elongation machinery
por: Gudipaty, Swapna Aravind, et al.
Publicado: (2016)

Phosphatidylinositol phosphate kinase PIPKIγ and phosphatase INPP5E coordinate initiation of ciliogenesis
por: Xu, Qingwen, et al.
Publicado: (2016)

Protein phosphatase PPM1A inhibition attenuates osteoarthritis via regulating TGF-β/Smad2 signaling in chondrocytes
por: Ge, Qinwen, et al.
Publicado: (2023)

Inhibition of lipid droplet formation by Ser/Thr protein phosphatase PPM1D inhibitor, SL-176
por: Kamada, Rui, et al.
Publicado: (2019)

The phosphatase PPM1A inhibits triple negative breast cancer growth by blocking cell cycle progression
por: Mazumdar, Abhijit, et al.
Publicado: (2019)

Expression of yeast lipid phosphatase Sac1p is regulated by phosphatidylinositol-4-phosphate
por: Knödler, Andreas, et al.
Publicado: (2008)

Association of PPM1G methylation with risk-taking in alcohol use disorder
por: Park, Chun Il, et al.
Publicado: (2020)

Gain-of-function mutations of PPM1D/Wip1 impair the p53-dependent G1 checkpoint
por: Kleiblova, Petra, et al.
Publicado: (2013)

Protein Phosphatase Magnesium-Dependent 1δ (PPM1D) Expression as a Prognostic Marker in Adult Supratentorial Diffuse Astrocytic and Oligodendroglial Tumors
por: Jeong, Hui Jeong, et al.
Publicado: (2018)

PPM1D/WIP1 in medulloblastoma
por: Akamandisa, Mwangala P., et al.
Publicado: (2016)

Inhibition of the DNA damage response phosphatase PPM1D reprograms neutrophils to enhance anti-tumor immune responses
por: Uyanik, Burhan, et al.
Publicado: (2021)

Involvement of Phosphatidylinositol 3-kinase in the regulation of proline catabolism in Arabidopsis thaliana
por: Leprince, Anne-Sophie, et al.
Publicado: (2015)

PPM-1, a PP2Cα/β phosphatase, Regulates Axon Termination and Synapse Formation in Caenorhabditis elegans
por: Tulgren, Erik D., et al.
Publicado: (2011)

PPM1D phosphatase, a target of p53 and RBM38 RNA-binding protein, inhibits p53 mRNA translation via dephosphorylation of RBM38
por: Zhang, Min, et al.
Publicado: (2015)

Phosphatase PPM1A negatively regulates P-TEFb function in resting CD4(+) T cells and inhibits HIV-1 gene expression
por: Budhiraja, Sona, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_pgfj8ql0vi648ibp8fpte6ph60