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Phosphatidylinositol-3 kinase-dependent translational regulation of Id1 involves the PPM1G phosphatase

Id1 is a helix-loop-helix transcriptional modulator that increases the aggressiveness of malignant glial neoplasms. Since most glioblastomas (GBMs) show increased phosphatidylinositol-3 kinase (PI-3K) signaling, we sought to determine whether this pathway regulates Id1 expression. Higher basal Id1 e...

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Detalles Bibliográficos
Autores principales:	Xu, Kaiming, Wang, Lanfang, Feng, Wei, Feng, Yue, Shu, Hui-Kuo G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064830/ https://www.ncbi.nlm.nih.gov/pubmed/27065332 http://dx.doi.org/10.1038/onc.2016.115

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