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SOX2 Is the Determining Oncogenic Switch in Promoting Lung Squamous Cell Carcinoma from Different Cells of Origin

Lung squamous cell carcinoma (LSCC) is a devastating malignancy with no effective treatments, due to its complex genomic profile. Therefore, preclinical models mimicking its salient features are urgently needed. Here we describe mouse models bearing various combinations of genetic lesions predominan...

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Detalles Bibliográficos
Autores principales:	Ferone, Giustina, Song, Ji-Ying, Sutherland, Kate D., Bhaskaran, Rajith, Monkhorst, Kim, Lambooij, Jan-Paul, Proost, Natalie, Gargiulo, Gaetano, Berns, Anton
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065004/ https://www.ncbi.nlm.nih.gov/pubmed/27728803 http://dx.doi.org/10.1016/j.ccell.2016.09.001

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