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The cystine/glutamate antiporter system x(c)(−) drives breast tumor cell glutamate release and cancer-induced bone pain

Bone is one of the leading sites of metastasis for frequently diagnosed malignancies, including those arising in the breast, prostate and lung. Although these cancers develop unnoticed and are painless in their primary sites, bone metastases result in debilitating pain. Deeper investigation of this...

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Detalles Bibliográficos
Autores principales: Slosky, Lauren M., BassiriRad, Neemah M., Symons, Ashley M., Thompson, Michelle, Doyle, Timothy, Forte, Brittany L., Staatz, William D., Bui, Lynn, Neumann, William L., Mantyh, Patrick W., Salvemini, Daniela, Largent-Milnes, Tally M., Vanderah, Todd W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065056/
https://www.ncbi.nlm.nih.gov/pubmed/27482630
http://dx.doi.org/10.1097/j.pain.0000000000000681