High-Resolution 4C Reveals Rapid p53-Dependent Chromatin Reorganization of the CDKN1A Locus in Response to Stress

A regulatory program involving hundreds of genes is coordinated by p53 to prevent carcinogenesis in response to stress. Given the importance of chromatin loops in gene regulation, we investigated whether DNA interactions participate in the p53 stress response. To shed light on this issue, we measure...

Descripción completa

Detalles Bibliográficos
Autores principales: Millau, Jean-François, Wijchers, Patrick, Gaudreau, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065170/
https://www.ncbi.nlm.nih.gov/pubmed/27741251
http://dx.doi.org/10.1371/journal.pone.0163885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065170/
https://www.ncbi.nlm.nih.gov/pubmed/27741251
http://dx.doi.org/10.1371/journal.pone.0163885

Ejemplares similares