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Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate

TGFβs act through canonical and non-canonical pathways, and canonical signals are transduced via Smad2 and Smad3. However, the contribution of canonical vs. non-canonical pathways in cartilage is unknown because the role of Smad2 in chondrogenesis has not been investigated in vivo. Therefore, we ana...

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Detalles Bibliográficos
Autores principales:	Wang, Weiguang, Song, Buer, Anbarchian, Teni, Shirazyan, Anna, Sadik, Joshua E., Lyons, Karen M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065210/ https://www.ncbi.nlm.nih.gov/pubmed/27741240 http://dx.doi.org/10.1371/journal.pgen.1006352

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