Cargando…

Detection and Management of Geographic Disparities in the TOPCAT Trial: Lessons Learned and Derivative Recommendations

TOPCAT (Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist Trial) was a multinational clinical trial of 3,445 heart failure with preserved ejection fraction patients that enrolled in 233 sites in 6 countries in North America, Eastern Europe, and South America. Patie...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bristow, Michael R., Silva Enciso, Jorge, Gersh, Bernard J., Grady, Christine, Rice, Madeline Murguia, Singh, Steven, Sopko, George, Boineau, Robin, Rosenberg, Yves, Greenberg, Barry H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	TRANSLATIONAL PERSPECTIVE
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065247/ https://www.ncbi.nlm.nih.gov/pubmed/27747305 http://dx.doi.org/10.1016/j.jacbts.2016.03.001

Ejemplares similares

Closer to or Farther away from an Ideal Model of Care? Lessons Learned from Geographic Cohorting
por: Kara, Areeba, et al.
Publicado: (2022)

Research Opportunities in Autonomic Neural Mechanisms of Cardiopulmonary Regulation: A Report From the National Heart, Lung, and Blood Institute and the National Institutes of Health Office of the Director Workshop
por: Mehra, Reena, et al.
Publicado: (2022)

Developing Course-Based Research Experiences in Discipline-Based Education Research: Lessons Learned and Recommendations
por: Cooper, Katelyn M., et al.
Publicado: (2018)

TOPCAT misses its primary endpoint: Should spironolactone be abandoned in HFpEF?
por: ElGuindy, Ahmed M.
Publicado: (2013)

Recommendations for the application and follow-up of quality controls in medical laboratories
por: Giannoli, Jean-Marc, et al.
Publicado: (2021)

Bias at warp speed: how AI may contribute to the disparities gap in the time of COVID-19
por: Röösli, Eliane, et al.
Publicado: (2020)

Effectively Addressing Human Immunodeficiency Virus Disparities Affecting US Black Women
por: Bradley, Erin L.P., et al.
Publicado: (2018)

COVID-19 Healthcare Inequity: Lessons Learned from Annual Influenza Vaccination Rates to Mitigate COVID-19 Vaccine Disparities
por: Bazan, Isabel S., et al.
Publicado: (2021)

Clinical implication of pulmonary hospitalization in heart failure with preserved ejection fraction: from the TOPCAT
por: Dong, Bin, et al.
Publicado: (2020)

Targeting efficacy of spironolactone in patients with heart failure with preserved ejection fraction: the TOPCAT study
por: Zhou, Hui‐min, et al.
Publicado: (2022)

Variations on fetal heart rate variability
por: Shaw, C. J., et al.
Publicado: (2016)

Failure to Launch: Targeting Inflammation in Acute Coronary Syndromes
por: Rymer, Jennifer A., et al.
Publicado: (2017)

Advances in Cardiovascular Care: How to Stimulate Innovation While Controlling Cost
por: Weintraub, William S., et al.
Publicado: (2018)

Molecular Epidemiology of Heart Failure: Translational Challenges and Opportunities
por: Smith, J. Gustav
Publicado: (2017)

Potentiation of Insulin Signaling Contributes to Heart Failure in Type 2 Diabetes: A Hypothesis Supported by Both Mechanistic Studies and Clinical Trials
por: Packer, Milton
Publicado: (2018)

Pharmacogenetic Labeling of FDA-Approved Drugs: A Regulatory Retrospective
por: Drozda, Katarzyna, et al.
Publicado: (2018)

Commentary: Renal Nerve Denervation: Is Renervation an Issue?
por: Rothstein, Marcos
Publicado: (2016)

A Perspective on the Delivery of Renal Denervation Therapy Based on Pre-Clinical Data
por: Tellez, Armando, et al.
Publicado: (2016)

Needs-Based Innovation in Cardiovascular Medicine: The Stanford Biodesign Process
por: Schwartz, Jonathan G., et al.
Publicado: (2016)

Temporal Trends and Factors Associated With Cardiovascular Drug Development, 1990 to 2012
por: Hwang, Thomas J., et al.
Publicado: (2016)

Stress‐testing the brain to understand its breaking points
por: Parrish, R. Ryley, et al.
Publicado: (2018)

Like sheep, like humans? Right ventricular remodelling in a preterm‐born ovine model
por: Mohamed, Afifah, et al.
Publicado: (2018)

Chest Compressions During Sustained Inflation During Cardiopulmonary Resuscitation in Newborn Infants Translating Evidence From Animal Studies to the Bedside
por: Schmölzer, Georg M.
Publicado: (2019)

Overcoming Barriers to Development of Novel Therapies for Cardiovascular Disease: Insights From the Oncology Drug Development Experience
por: Khakoo, Aarif Y., et al.
Publicado: (2019)

Mendelian Randomization Studies Promise to Shorten the Journey to FDA Approval
por: Roberts, Robert
Publicado: (2018)

Translation of Cardiac Myosin Activation With 2-Deoxy-ATP to Treat Heart Failure Via an Experimental Ribonucleotide Reductase-Based Gene Therapy
por: Thomson, Kassandra S., et al.
Publicado: (2016)

Advancing the Science of Myocardial Recovery With Mechanical Circulatory Support: A Working Group of the National, Heart, Lung, and Blood Institute
por: Drakos, Stavros G., et al.
Publicado: (2017)

Multiorgan Damage in Patients With COVID-19: Is the TGF-β/BMP Pathway the Missing Link?
por: Carlson, F. Roy, et al.
Publicado: (2020)

“Warp Speed” Operations in the COVID-19 Pandemic: Moving Too Quickly?
por: Van Norman, Gail A.
Publicado: (2020)

RNA Vaccines for COVID-19: 5 Things Every Cardiologist Should Know
por: Lin, Chien-Jung, et al.
Publicado: (2020)

Limitations of Animal Studies for Predicting Toxicity in Clinical Trials: Is it Time to Rethink Our Current Approach?
por: Van Norman, Gail A.
Publicado: (2019)

The Heart in COVID-19: Primary Target or Secondary Bystander?
por: Libby, Peter
Publicado: (2020)

Apolipoprotein A-I for Cardiac Recovery Post–Myocardial Infarction
por: Richart, Adele L., et al.
Publicado: (2021)

Von Willebrand Factor Activity in Thrombosis: An Overlooked Target for Intervention?
por: Shalmi, Theodor W., et al.
Publicado: (2021)

MicroRNA-Based Diagnostics in Heart Diseases: Current Limitations and Future Perspectives
por: Düsing, Philip, et al.
Publicado: (2021)

CARD9-Mediated Signaling and Cardiovascular Diseases
por: Liu, Xuanyou, et al.
Publicado: (2022)

Decentralized Clinical Trials: The Future of Medical Product Development?∗
por: Van Norman, Gail A.
Publicado: (2021)

DAPA-CKD: The Beginning of a New Era in Renal Protection
por: Cherney, David Z.I., et al.
Publicado: (2021)

The CNP/NPR-B/cGMP Axis is a Therapeutic Target in Calcific Aortic Stenosis
por: Armstrong, David W.J., et al.
Publicado: (2021)

Maintaining Success for Patients With Dilated Cardiomyopathy and Remission of Heart Failure
por: Halliday, Brian P., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ua2oodgc7kukrmf07hdlfhha93