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miR-29b overexpression induces cochlear hair cell apoptosis through the regulation of SIRT1/PGC-1α signaling: Implications for age-related hearing loss

It has been reported that the degeneration of cochlear hair cells is the typical cause of presbycusis (or age-related hearing loss). However, the molecular mechanisms that mediate cochlear hair cell apoptosis are not yet fully understood and there is no effective treatment for this disorder. MicroRN...

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Detalles Bibliográficos
Autores principales: Xue, Tao, Wei, Li, Zha, Ding-Jun, Qiu, Jian-Hua, Chen, Fu-Quan, Qiao, Li, Qiu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065299/
https://www.ncbi.nlm.nih.gov/pubmed/27635430
http://dx.doi.org/10.3892/ijmm.2016.2735