The First Case of Severe Takotsubo Cardiomyopathy Associated with 5-Fluorouracil in a Patient with Abnormalities of Both Dihydropyrimidine Dehydrogenase (DPYD) and Thymidylate Synthase (TYMS) Genes

5-Fluorouracil (5-FU) is the backbone of the chemotherapy regimens approved for treatment of many malignancies, especially colorectal cancer (CRC). The incidence of cardiotoxicity associated with 5-FU ranges between 1.5% to 18% and is most commonly manifested as anginal symptoms. Cardiomyopathy is v...

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Detalles Bibliográficos
Autores principales: Saif, Muhammad W, Smith, Melissa, Maloney, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2016
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065345/
https://www.ncbi.nlm.nih.gov/pubmed/27752409
http://dx.doi.org/10.7759/cureus.783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065345/
https://www.ncbi.nlm.nih.gov/pubmed/27752409
http://dx.doi.org/10.7759/cureus.783

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