The effect of losartan therapy on ventricular function in Marfan patients with haploinsufficient or dominant negative FBN1 mutations

BACKGROUND: Mild biventricular dysfunction is often present in patients with Marfan syndrome. Losartan has been shown to reduce aortic dilatation in patients with Marfan syndrome. This study assesses the effect of losartan on ventricular volume and function in genetically classified subgroups of asy...

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Detalles Bibliográficos
Autores principales: den Hartog, A. W., Franken, R., van den Berg, M. P., Zwinderman, A. H., Timmermans, J., Scholte, A. J., de Waard, V., Spijkerboer, A. M., Pals, G., Mulder, B. J. M., Groenink, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bohn Stafleu van Loghum 2016
Materias:
Original Article – Point of View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065542/
https://www.ncbi.nlm.nih.gov/pubmed/27704402
http://dx.doi.org/10.1007/s12471-016-0905-8

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