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From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics: meeting report from the third international symposium on “New frontiers in cardiovascular research”
In this meeting report, particularly addressing the topic of protection of the cardiovascular system from ischemia/reperfusion injury, highlights are presented that relate to conditioning strategies of the heart with respect to molecular mechanisms and outcome in patients’ cohorts, the influence of...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065587/ https://www.ncbi.nlm.nih.gov/pubmed/27743118 http://dx.doi.org/10.1007/s00395-016-0586-x |
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author | Cabrera-Fuentes, Hector A. Aragones, Julian Bernhagen, Jürgen Boening, Andreas Boisvert, William A. Bøtker, Hans E. Bulluck, Heerajnarain Cook, Stuart Di Lisa, Fabio Engel, Felix B. Engelmann, Bernd Ferrazzi, Fulvia Ferdinandy, Péter Fong, Alan Fleming, Ingrid Gnaiger, Erich Hernández-Reséndiz, Sauri Kalkhoran, Siavash Beikoghli Kim, Moo Hyun Lecour, Sandrine Liehn, Elisa A. Marber, Michael S. Mayr, Manuel Miura, Tetsuji Ong, Sang-Bing Peter, Karlheinz Sedding, Daniel Singh, Manvendra K. Suleiman, M. Saadeh Schnittler, Hans J. Schulz, Rainer Shim, Winston Tello, Daniel Vogel, Carl-Wilhelm Walker, Malcolm Li, Qilong Oscar Yang Yellon, Derek M. Hausenloy, Derek J. Preissner, Klaus T. |
author_facet | Cabrera-Fuentes, Hector A. Aragones, Julian Bernhagen, Jürgen Boening, Andreas Boisvert, William A. Bøtker, Hans E. Bulluck, Heerajnarain Cook, Stuart Di Lisa, Fabio Engel, Felix B. Engelmann, Bernd Ferrazzi, Fulvia Ferdinandy, Péter Fong, Alan Fleming, Ingrid Gnaiger, Erich Hernández-Reséndiz, Sauri Kalkhoran, Siavash Beikoghli Kim, Moo Hyun Lecour, Sandrine Liehn, Elisa A. Marber, Michael S. Mayr, Manuel Miura, Tetsuji Ong, Sang-Bing Peter, Karlheinz Sedding, Daniel Singh, Manvendra K. Suleiman, M. Saadeh Schnittler, Hans J. Schulz, Rainer Shim, Winston Tello, Daniel Vogel, Carl-Wilhelm Walker, Malcolm Li, Qilong Oscar Yang Yellon, Derek M. Hausenloy, Derek J. Preissner, Klaus T. |
author_sort | Cabrera-Fuentes, Hector A. |
collection | PubMed |
description | In this meeting report, particularly addressing the topic of protection of the cardiovascular system from ischemia/reperfusion injury, highlights are presented that relate to conditioning strategies of the heart with respect to molecular mechanisms and outcome in patients’ cohorts, the influence of co-morbidities and medications, as well as the contribution of innate immune reactions in cardioprotection. Moreover, developmental or systems biology approaches bear great potential in systematically uncovering unexpected components involved in ischemia–reperfusion injury or heart regeneration. Based on the characterization of particular platelet integrins, mitochondrial redox-linked proteins, or lipid-diol compounds in cardiovascular diseases, their targeting by newly developed theranostics and technologies opens new avenues for diagnosis and therapy of myocardial infarction to improve the patients’ outcome. |
format | Online Article Text |
id | pubmed-5065587 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-50655872016-10-28 From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics: meeting report from the third international symposium on “New frontiers in cardiovascular research” Cabrera-Fuentes, Hector A. Aragones, Julian Bernhagen, Jürgen Boening, Andreas Boisvert, William A. Bøtker, Hans E. Bulluck, Heerajnarain Cook, Stuart Di Lisa, Fabio Engel, Felix B. Engelmann, Bernd Ferrazzi, Fulvia Ferdinandy, Péter Fong, Alan Fleming, Ingrid Gnaiger, Erich Hernández-Reséndiz, Sauri Kalkhoran, Siavash Beikoghli Kim, Moo Hyun Lecour, Sandrine Liehn, Elisa A. Marber, Michael S. Mayr, Manuel Miura, Tetsuji Ong, Sang-Bing Peter, Karlheinz Sedding, Daniel Singh, Manvendra K. Suleiman, M. Saadeh Schnittler, Hans J. Schulz, Rainer Shim, Winston Tello, Daniel Vogel, Carl-Wilhelm Walker, Malcolm Li, Qilong Oscar Yang Yellon, Derek M. Hausenloy, Derek J. Preissner, Klaus T. Basic Res Cardiol Meeting Report In this meeting report, particularly addressing the topic of protection of the cardiovascular system from ischemia/reperfusion injury, highlights are presented that relate to conditioning strategies of the heart with respect to molecular mechanisms and outcome in patients’ cohorts, the influence of co-morbidities and medications, as well as the contribution of innate immune reactions in cardioprotection. Moreover, developmental or systems biology approaches bear great potential in systematically uncovering unexpected components involved in ischemia–reperfusion injury or heart regeneration. Based on the characterization of particular platelet integrins, mitochondrial redox-linked proteins, or lipid-diol compounds in cardiovascular diseases, their targeting by newly developed theranostics and technologies opens new avenues for diagnosis and therapy of myocardial infarction to improve the patients’ outcome. Springer Berlin Heidelberg 2016-10-14 2016 /pmc/articles/PMC5065587/ /pubmed/27743118 http://dx.doi.org/10.1007/s00395-016-0586-x Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Meeting Report Cabrera-Fuentes, Hector A. Aragones, Julian Bernhagen, Jürgen Boening, Andreas Boisvert, William A. Bøtker, Hans E. Bulluck, Heerajnarain Cook, Stuart Di Lisa, Fabio Engel, Felix B. Engelmann, Bernd Ferrazzi, Fulvia Ferdinandy, Péter Fong, Alan Fleming, Ingrid Gnaiger, Erich Hernández-Reséndiz, Sauri Kalkhoran, Siavash Beikoghli Kim, Moo Hyun Lecour, Sandrine Liehn, Elisa A. Marber, Michael S. Mayr, Manuel Miura, Tetsuji Ong, Sang-Bing Peter, Karlheinz Sedding, Daniel Singh, Manvendra K. Suleiman, M. Saadeh Schnittler, Hans J. Schulz, Rainer Shim, Winston Tello, Daniel Vogel, Carl-Wilhelm Walker, Malcolm Li, Qilong Oscar Yang Yellon, Derek M. Hausenloy, Derek J. Preissner, Klaus T. From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics: meeting report from the third international symposium on “New frontiers in cardiovascular research” |
title | From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics: meeting report from the third international symposium on “New frontiers in cardiovascular research” |
title_full | From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics: meeting report from the third international symposium on “New frontiers in cardiovascular research” |
title_fullStr | From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics: meeting report from the third international symposium on “New frontiers in cardiovascular research” |
title_full_unstemmed | From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics: meeting report from the third international symposium on “New frontiers in cardiovascular research” |
title_short | From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics: meeting report from the third international symposium on “New frontiers in cardiovascular research” |
title_sort | from basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics: meeting report from the third international symposium on “new frontiers in cardiovascular research” |
topic | Meeting Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065587/ https://www.ncbi.nlm.nih.gov/pubmed/27743118 http://dx.doi.org/10.1007/s00395-016-0586-x |
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