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Structure-mechanism-based engineering of chemical regulators targeting distinct pathological factors in Alzheimer's disease

The absence of effective therapeutics against Alzheimer's disease (AD) is a result of the limited understanding of its multifaceted aetiology. Because of the lack of chemical tools to identify pathological factors, investigations into AD pathogenesis have also been insubstantial. Here we report...

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Detalles Bibliográficos
Autores principales:	Beck, Michael W., Derrick, Jeffrey S., Kerr, Richard A., Oh, Shin Bi, Cho, Woo Jong, Lee, Shin Jung C., Ji, Yonghwan, Han, Jiyeon, Tehrani, Zahra Aliakbar, Suh, Nayoung, Kim, Sujeong, Larsen, Scott D., Kim, Kwang S., Lee, Joo-Yong, Ruotolo, Brandon T., Lim, Mi Hee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065625/ https://www.ncbi.nlm.nih.gov/pubmed/27734843 http://dx.doi.org/10.1038/ncomms13115

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