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Impaired vascular function in sepsis-surviving rats mediated by oxidative stress and Rho-Kinase pathway
We investigated long-lasting changes in endothelial and vascular function in adult rat survivors of severe sepsis induced by cecal ligation and puncture (CLP) model. For this, male Wistar rats (200–350 g) had their cecum punctured once (non-transfixing hole) with a 14-gauge needle. Performed in this...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065648/ https://www.ncbi.nlm.nih.gov/pubmed/27744119 http://dx.doi.org/10.1016/j.redox.2016.09.016 |