Cargando…

The extreme capsule fiber complex in humans and macaque monkeys: a comparative diffusion MRI tractography study

We compared the course and cortical projections of white matter fibers passing through the extreme capsule in humans and macaques. Previous comparisons of this tract have suggested a uniquely human posterior projection, but these studies have always employed different techniques in the different spe...

Descripción completa

Detalles Bibliográficos
Autores principales: Mars, Rogier B., Foxley, Sean, Verhagen, Lennart, Jbabdi, Saad, Sallet, Jérôme, Noonan, MaryAnn P., Neubert, Franz-Xaver, Andersson, Jesper L., Croxson, Paula L., Dunbar, Robin I. M., Khrapitchev, Alexandre A., Sibson, Nicola R., Miller, Karla L., Rushworth, Matthew F. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065901/
https://www.ncbi.nlm.nih.gov/pubmed/26627483
http://dx.doi.org/10.1007/s00429-015-1146-0
_version_ 1782460382691983360
author Mars, Rogier B.
Foxley, Sean
Verhagen, Lennart
Jbabdi, Saad
Sallet, Jérôme
Noonan, MaryAnn P.
Neubert, Franz-Xaver
Andersson, Jesper L.
Croxson, Paula L.
Dunbar, Robin I. M.
Khrapitchev, Alexandre A.
Sibson, Nicola R.
Miller, Karla L.
Rushworth, Matthew F. S.
author_facet Mars, Rogier B.
Foxley, Sean
Verhagen, Lennart
Jbabdi, Saad
Sallet, Jérôme
Noonan, MaryAnn P.
Neubert, Franz-Xaver
Andersson, Jesper L.
Croxson, Paula L.
Dunbar, Robin I. M.
Khrapitchev, Alexandre A.
Sibson, Nicola R.
Miller, Karla L.
Rushworth, Matthew F. S.
author_sort Mars, Rogier B.
collection PubMed
description We compared the course and cortical projections of white matter fibers passing through the extreme capsule in humans and macaques. Previous comparisons of this tract have suggested a uniquely human posterior projection, but these studies have always employed different techniques in the different species. Here we used the same technique, diffusion MRI, in both species to avoid attributing differences in techniques to differences in species. Diffusion MRI-based probabilistic tractography was performed from a seed area in the extreme capsule in both human and macaques. We compared in vivo data of humans and macaques as well as one high-resolution ex vivo macaque dataset. Tractography in the macaque was able to replicate most results known from macaque tracer studies, including selective innervation of frontal cortical areas and targets in the superior temporal cortex. In addition, however, we also observed some tracts that are not commonly reported in macaque tracer studies and that are more reminiscent of results previously only reported in the human. In humans, we show that the ventrolateral prefrontal cortex innervations are broadly similar to those in the macaque. These results suggest that evolutionary changes in the human extreme capsule fiber complex are likely more gradual than punctuated. Further, they demonstrate both the potential and limitations of diffusion MRI tractography.
format Online
Article
Text
id pubmed-5065901
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Springer Berlin Heidelberg
record_format MEDLINE/PubMed
spelling pubmed-50659012016-10-28 The extreme capsule fiber complex in humans and macaque monkeys: a comparative diffusion MRI tractography study Mars, Rogier B. Foxley, Sean Verhagen, Lennart Jbabdi, Saad Sallet, Jérôme Noonan, MaryAnn P. Neubert, Franz-Xaver Andersson, Jesper L. Croxson, Paula L. Dunbar, Robin I. M. Khrapitchev, Alexandre A. Sibson, Nicola R. Miller, Karla L. Rushworth, Matthew F. S. Brain Struct Funct Original Article We compared the course and cortical projections of white matter fibers passing through the extreme capsule in humans and macaques. Previous comparisons of this tract have suggested a uniquely human posterior projection, but these studies have always employed different techniques in the different species. Here we used the same technique, diffusion MRI, in both species to avoid attributing differences in techniques to differences in species. Diffusion MRI-based probabilistic tractography was performed from a seed area in the extreme capsule in both human and macaques. We compared in vivo data of humans and macaques as well as one high-resolution ex vivo macaque dataset. Tractography in the macaque was able to replicate most results known from macaque tracer studies, including selective innervation of frontal cortical areas and targets in the superior temporal cortex. In addition, however, we also observed some tracts that are not commonly reported in macaque tracer studies and that are more reminiscent of results previously only reported in the human. In humans, we show that the ventrolateral prefrontal cortex innervations are broadly similar to those in the macaque. These results suggest that evolutionary changes in the human extreme capsule fiber complex are likely more gradual than punctuated. Further, they demonstrate both the potential and limitations of diffusion MRI tractography. Springer Berlin Heidelberg 2015-12-01 2016 /pmc/articles/PMC5065901/ /pubmed/26627483 http://dx.doi.org/10.1007/s00429-015-1146-0 Text en © The Author(s) 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Article
Mars, Rogier B.
Foxley, Sean
Verhagen, Lennart
Jbabdi, Saad
Sallet, Jérôme
Noonan, MaryAnn P.
Neubert, Franz-Xaver
Andersson, Jesper L.
Croxson, Paula L.
Dunbar, Robin I. M.
Khrapitchev, Alexandre A.
Sibson, Nicola R.
Miller, Karla L.
Rushworth, Matthew F. S.
The extreme capsule fiber complex in humans and macaque monkeys: a comparative diffusion MRI tractography study
title The extreme capsule fiber complex in humans and macaque monkeys: a comparative diffusion MRI tractography study
title_full The extreme capsule fiber complex in humans and macaque monkeys: a comparative diffusion MRI tractography study
title_fullStr The extreme capsule fiber complex in humans and macaque monkeys: a comparative diffusion MRI tractography study
title_full_unstemmed The extreme capsule fiber complex in humans and macaque monkeys: a comparative diffusion MRI tractography study
title_short The extreme capsule fiber complex in humans and macaque monkeys: a comparative diffusion MRI tractography study
title_sort extreme capsule fiber complex in humans and macaque monkeys: a comparative diffusion mri tractography study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065901/
https://www.ncbi.nlm.nih.gov/pubmed/26627483
http://dx.doi.org/10.1007/s00429-015-1146-0
work_keys_str_mv AT marsrogierb theextremecapsulefibercomplexinhumansandmacaquemonkeysacomparativediffusionmritractographystudy
AT foxleysean theextremecapsulefibercomplexinhumansandmacaquemonkeysacomparativediffusionmritractographystudy
AT verhagenlennart theextremecapsulefibercomplexinhumansandmacaquemonkeysacomparativediffusionmritractographystudy
AT jbabdisaad theextremecapsulefibercomplexinhumansandmacaquemonkeysacomparativediffusionmritractographystudy
AT salletjerome theextremecapsulefibercomplexinhumansandmacaquemonkeysacomparativediffusionmritractographystudy
AT noonanmaryannp theextremecapsulefibercomplexinhumansandmacaquemonkeysacomparativediffusionmritractographystudy
AT neubertfranzxaver theextremecapsulefibercomplexinhumansandmacaquemonkeysacomparativediffusionmritractographystudy
AT anderssonjesperl theextremecapsulefibercomplexinhumansandmacaquemonkeysacomparativediffusionmritractographystudy
AT croxsonpaulal theextremecapsulefibercomplexinhumansandmacaquemonkeysacomparativediffusionmritractographystudy
AT dunbarrobinim theextremecapsulefibercomplexinhumansandmacaquemonkeysacomparativediffusionmritractographystudy
AT khrapitchevalexandrea theextremecapsulefibercomplexinhumansandmacaquemonkeysacomparativediffusionmritractographystudy
AT sibsonnicolar theextremecapsulefibercomplexinhumansandmacaquemonkeysacomparativediffusionmritractographystudy
AT millerkarlal theextremecapsulefibercomplexinhumansandmacaquemonkeysacomparativediffusionmritractographystudy
AT rushworthmatthewfs theextremecapsulefibercomplexinhumansandmacaquemonkeysacomparativediffusionmritractographystudy
AT marsrogierb extremecapsulefibercomplexinhumansandmacaquemonkeysacomparativediffusionmritractographystudy
AT foxleysean extremecapsulefibercomplexinhumansandmacaquemonkeysacomparativediffusionmritractographystudy
AT verhagenlennart extremecapsulefibercomplexinhumansandmacaquemonkeysacomparativediffusionmritractographystudy
AT jbabdisaad extremecapsulefibercomplexinhumansandmacaquemonkeysacomparativediffusionmritractographystudy
AT salletjerome extremecapsulefibercomplexinhumansandmacaquemonkeysacomparativediffusionmritractographystudy
AT noonanmaryannp extremecapsulefibercomplexinhumansandmacaquemonkeysacomparativediffusionmritractographystudy
AT neubertfranzxaver extremecapsulefibercomplexinhumansandmacaquemonkeysacomparativediffusionmritractographystudy
AT anderssonjesperl extremecapsulefibercomplexinhumansandmacaquemonkeysacomparativediffusionmritractographystudy
AT croxsonpaulal extremecapsulefibercomplexinhumansandmacaquemonkeysacomparativediffusionmritractographystudy
AT dunbarrobinim extremecapsulefibercomplexinhumansandmacaquemonkeysacomparativediffusionmritractographystudy
AT khrapitchevalexandrea extremecapsulefibercomplexinhumansandmacaquemonkeysacomparativediffusionmritractographystudy
AT sibsonnicolar extremecapsulefibercomplexinhumansandmacaquemonkeysacomparativediffusionmritractographystudy
AT millerkarlal extremecapsulefibercomplexinhumansandmacaquemonkeysacomparativediffusionmritractographystudy
AT rushworthmatthewfs extremecapsulefibercomplexinhumansandmacaquemonkeysacomparativediffusionmritractographystudy